Detection of Mycobacterium tuberculosis Based on H37Rv Binding Peptides Using Surface Functionalized Magnetic Microspheres Coupled with Quantum Dots - A Nano Detection Method for Mycobacterium Tuberculosis

Yang H, et al., 10:77-88, Int J Nanomedicinev, 2015

This article describes the generation of phage display derived peptide ligands for Mycobacterium tuberculosis (MTB) cells with improved limit of detection (LOD) and specificity. A Pall ForteBio Octet QK system equipped with Streptavidin biosensors was used to capture biotinylated peptides. The bacteria binding events were monitored in real time to determine affinity and specificity for H37Rv, BCG , P. aeruginosa, and E. coli.

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