Sensor Domain of Histidine Kinase KinB of Pseudomonas A HELIX-SWAPPED DIMER

Tan K, et al., 289(18):12232-44, J Biol Chem, 2014

The authors generated structural, mutagenesis, computational and biophysical data to examine the signaling molecules that interact with KinB, a histidine kinase that acts as a negative regulator of alginate biosynthesis in Psduodomas aeruginosa and to better understand the signal transduction mechanism. Binding studies were performed on the Octet RED system and Super Streptavidin biosensors were used.

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