Screening and Optimization of Chemically Defined Media and Feeds with Integrated and Statistical Approaches

Xiao Z, et al., 1104, 117-35, Methods Mol Biol, 2014

The authors described a case study detailing the design of experiment and revised workflow to improve titer and protein yields by varying culture media selection and feeding conditions performed by bioprocessing and production groups for batch culturing of cells. Protein titers were determined using the Octet QK system and custom biosensors.

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