Publications

Receptor Binding by H10 Influenza Viruses

Vachieri SG, et al., 511(7510):475-7, Nature, 2014

The authors performed structural and functional analysis to better understand the binding and receptor interaction characteristics of the H10 influenza virus from avians and humans as the avian H10N8 virus has sufficient avidity for human receptors. However, it is the presence of mucins in the human airway and a lack of mutations to the H10 haemagglutinin that need to be constantly monitored to prevent transmission between humans. Binding studies were performed on the Octet RED system and Streptavidin biosensors were used.

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