Production and Characterization of Recombinant Human Beta-defensin DEFB120

Liu H, et al., doi: 10.1002/psc.2611, J Pept Sci, 2014

The authors performed structural and biological characterization on recombinantly generated DEFB120, a novel human beta-defensin protein. Beta defensins are involved in innate immunity and represent a new class of possible therapeutics to be developed that can overcome the evolving multi-antibiotic resistances of many strains. Detection and interaction between DEFB120 and LPS was carried out on the Octet RED96 system using Streptavidin biosensors.

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