Postnatally-transmitted HIV-1 Envelope Variants have Similar Neutralization-sensitivity and Function to that of Nontransmitted Breast Milk Variants

Fouda, G G, et al., 10(1), 3, Retrovirology, 2013

In this study, the authors compare the genotype and function of HIV-1 Env variants isolated for postnatally-transmitting mothers, clinically-matched nontransmitting mothers, and postnatally-infected infants. Binding of breast milk HIV-1 gp120 proteins expressed by milk ENV variants to Galcer liposomes was studied using the Octet RED system with Aminopropylsilane (APS) biosensors.

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