Molecular Mechanism of the Synaptotagmin-SNARE Interaction in Ca2+-Triggered Vesicle Fusion

Vrljic, M., et al., 17(3), 325-331, Nature Structural and Molecular Biology, 2010

This publication characterizes the interactions between SNARE complex and synaptotagmin, proteins involved in the fusion of vesicles in the plasma membrane of neurons. The SNARE-synaptotagmin 3 interaction was studied with the Octet RED platform using biotinylated synaptotagmin 3 immobilied on Streptavidin biosensors.

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