Publications

Lysine Acetylation is a Widespread Protein Modification for Diverse Proteins in Arabidopsis

Wu, X., et al., 155(4), 1769-1778, Plant Physiology, 2011

The authors describe a reversible protein posttranslational modification called Lysine Acetylation (LysAc), that is found to be widespread in small flowering plants called Arabidopsis. Their findings reveal the possibility that reversible LysAc may be an important and previously unknown regulatory mechanism affecting a wide range of cellular pathways and processes in Arabidopsis plants. The paper shows Octet QK system data comparing binding of Calmodulin to eEF peptide before and after acetylation of the lysine. Acetylation was shown to reduce the affinity of the protein-protein interaction.

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