Effects of Hyaluronic Acid Conjugation on Anti-TNF-α Inhibition of Inflammation in Burns

Friedrich E, et al., doi: 10.1002/jbm.a.34829, J Biomed Mater Res A, 2013

To elucidate the benefits of a topical antibody treatment, the authors compare the effectiveness of (anti-TNF-α)-hyaluronic acid conjugates to nonconjugated anti-TNF-α antibody and a non-conjugated mixture of hyaluronic acid and anti-TNF-α. Binding affinities were determined using the Octet QK system and biotinylated antibodies loaded onto Streptavidin biosensors.

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