Clearance Kinetics and Matrix Binding Partners of the Receptor for Advanced Glycation End Products

Milutinovic PS, et al., 9(3):e88259, PLoS One, 2014

The authors performed studies examining protein clearance kinetics and matrix binding protein interactions of the receptor for advanced glycation end products (RAGE), which is known to be a key player in numerous disease processes such as cardiomyopathy, inflammation, neurodegeneration and tumor invasion. Binding kinetics of RAGE to various matrix proteins were performed on the Octet system using Amine-Reactive biosensors.

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