Antibody Interactions with Ricinus Communis Agglutinins Studied by Biolayer Interferometry

Brandon D, et al., doi:10.1080/00032719.2014.886693, Anal Lett, 2014

The authors described the screening of several food matrices for mAbs to Ricin, a protein synthesized from castor plants that has been shown to have toxic effects. BLI was used to examine and confirm previously reported ELISA data on the binding characteristics of two ricin-specific mAbs suggesting this method is a potential immunodiagonostic for food matrices. Binding studies were performed on the Octet QK system. Amine-reactive (AR), Streptavidin and Anti-mouse Fc capture (AMC) biosensors were used in the experiments.

Read More