A High-throughput Media Design Approach for High Performance Mammalian Fed-batch Cultures

Rouiller, Y, et al., 5(3), 501-511, mAbs, 2013

The authors describe a new high-throughput blending method for batch-fed cell culture process media development. The method enabled optimization of all components of a CHO fed-batch medium in a single experiment. Titer determinations were performed using an Octet QKe system with Protein A biosensors.

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