ForteBio - Octet

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Determining kinetics and affinities of protein interactions using a parallel real-time label-free biosensor, the Octet

Y Abdiche, D Malashock, A Pinkerton, J Pons - Analytical biochemistry, 2008 - Elsevier

… Abstract. ForteBio's Octet optical biosensor harnesses biolayer interferometry to detect and quantify molecular interactions using disposable fiber-optic biosensors that address samples from an open shaking microplate without any microfluidics …

Cited by 266 Related articles All 5 versions

Exploring blocking assays using Octet, ProteOn, and Biacore biosensors

YN Abdiche, DS Malashock, A Pinkerton, J Pons - Analytical biochemistry, 2009 - Elsevier

… We describe three assay orientations that we term in tandem, premix, and classical sandwich blocking, and we perform each of them on three platforms: ForteBio's Octet QK, Bio-Rad's ProteOn XPR36, and GE Healthcare's Biacore 3000 …

Cited by 66 Related articles All 4 versions

Detection of low-affinity anti-drug antibodies and improved drug tolerance in immunogenicity testing by Octet® biolayer interferometry

J Li, A Schantz, M Schwegler, G Shankar - Journal of pharmaceutical and …, 2011 - Elsevier

… The Octet ® System (FortéBio, Inc., Menlo Park, CA) is another biosensor technology that employs a related BLI system (for a comprehensive review of the principles of BLI, the reader is referred to a prior publication [20] or the manufacturer's website …

Cited by 61 Related articles All 10 versions [PDF]

Biolayer Interferometry as an Alternative to HPLC for Measuring Product Concentration in Fermentation Broth

After the subcellular location for protein expression has been decided, the next challenge is the availability of an appropriate analytical method that can measure the concentration of the target analyte in complex matrices that fermentation broth usually offers (12)…