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Clone Screening

Clone screening systems for monoclonality verification and colony picking

Our solutions for antibody discovery and cell line development provide dedicated, scalable, and easy-to-use products for establishing clonal populations. The systems feature a selection of options and models to address your specific research including multiple imaging modes, biology-specific pins, fluidics, and environmental control. These solutions combine intelligent imaging with analysis and automation to increase throughput, consistency, and provide image-based documentation.

  • Verify monoclonality easily

    Objective selection, imaging, and data collection streamlines tracking of colony formation from a single cell.

  • Sort viable single cells efficiently

    High accuracy robotics combined with gentle fluidics-based systems establish viable clones with much higher efficiency.

  • Streamline workflows

    Automation with sample tracking increases throughput, allows for more walk-away time, and provides consistent results.

CloneSelect Single-Cell Printer

QPix 400 Series

Fully automate synthetic biology workflows for DNA assembly, antibody discovery and protein engineering

The QPix™ 400 Series Microbial Colony Pickers combine intelligent image analysis with precise automation for fast and efficient screening of large libraries. With a variety of data tracking and assay tools, the QPix Software streamlines the control and management of complex and iterative processes.

QPix 400 Series
    • Automate several sample prep and plate handling processes such as transfer of bacterial liquid culture and plating on agar
    • Streamline your workflow with scalable automation – pick up to 30,000 colonies per day
    • Electronic data tracking for well-documented data control
    • Sterile environment with customizable HEPA filtration options
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ClonePix Series

Automate antibody discovery and cell line development workflows

Screen more clones with the ClonePix™ Series in less time with monoclonal verification on day zero, then screen and pick for highest producers in weeks, not months.

ClonePix Series
    • Screen 10X more clones than limiting dilution
    • Increase probability of identifying high-value clones
    • Condense the workflow into a single solution
    • Eliminate or recover unstable clones early
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CloneSelect Imager

Verify monoclonality confidently

The CloneSelect™ Imager can help you meet regulatory demands of single cell verification with its automated analysis of cells in the white light channel. The system also enables concurrent confluence and monoclonality studies.

ClonePix Series
    • Document evidence of single cells and confluency digitally for auditing and submission to regulatory authorities
    • Image cells non invasively at multiple time points to monitor colony formation
    • Screen using high resolution white light imaging
    • Deliver real-time results with on-the-fly analysis
    • Automation and integration ready
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CloneSelect Single-Cell Printer††

Demonstrate monoclonality with greater confidence

The CloneSelect™ Single-Cell Printer™ (SCP series) by Cytena and Molecular Devices is a fully automated system that utilizes proprietary microfluidics-based technology and real-time image analysis to sort and deposit single cells into standard microplates—while simultaneously providing assurance of monoclonality through image documentation.

CloneSelect Single-Cell Printer

††Only available in North America, China, Hong Kong, and Taiwan

    • Confidently isolate single cells and provide consistent, high-quality image evidence of monoclonality to the FDA
    • Highly efficient single-cell sorting with an average printing efficiency > 80% observed when using CHO cells and HEK 293 cells
    • Achieve comparable high cell viability to limiting dilution method by gentle handling cells
    • Minimize cross contamination through disposable cell printing cartridges
    • Fast turnaround time—prints a 96-well plate within 5-10 minutes
    • Sort wide range of cell lines: CHO, HEK, SF9, iPSC, primary cells
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