Octet HTX offers unprecedented speed - antibody quantitation, kinetics, epitope binning, and much more

From IgG titer to epitope binning, the Octet HTX and Octet RED384 Systems offer label-free molecular interaction analysts with state-of-the-art high throughput platforms that facilitate the rapid characterization and development of biologics drug molecules.

  • Analyze up to 96 samples simultaneously

    Analyze up to 96 samples simultaneously

    Perform your quantitation or kinetics experiments with unmatched speed. Quantitate up to 96 samples of an IgG sample in two minutes.

  • Perform epitope binning

    Perform a 32 x 32 epitope binning in less than eight hours

    Use in-tandem, sandwich, or pre-mix assay designs to perform epitope binning. Complete a 32 x 32 epitope binning in less than eight hours.

  • Streamline workflows

    Streamline workflows with automation

    The Octet HTX and Octet RED384 are automation ready and are robot compatible for microplate and biosensor tray loading.

Automated workflow solutions for the Octet HTX and RED384 systems

Features

  • Microfluidics-free Dip and Read

    Microfluidics-free Dip and Read format reduces assay time and maintenance cost

    The Octet HTX and Octet RED384 utilize ForteBio's Dip and Read™ technology with the read head dipping into samples in a plate format. With no fluidics involved, Octet systems are highly robust.

  • Simultaneously reads 8, 16, 32, 48 or 96 wells

    Simultaneously reads 8, 16, 32, 48 or 96 wells

    The HTX read head provides design flexibility that allows users to analyze, 8, 16, 32, 48, or 96 samples at a time allowing for customized through put up to 96 samples.

  • Full plate off-rate ranking in minutes, not hours

    Full plate off-rate ranking in minutes, not hours

    The Dip and Read assay format allows off-rate analysis of clones to be performed rapidly even in crude samples using ready-to-use biosensors off the shelf.

  • 96-well plate quantitation

    96-well plate quantitation in as little as two minutes

    IgG titer determination of a full 96-well plate can be completed in two minutes. In addition, sample plate compartment is compatible with 384-well plates allowing for even more throughput.

  • epitope binning

    32 x 32 epitope binning in less than eight hours

    With the HTX, analysis of epitope binning matrices can be completed in record time, with 32 x 32 in less than eight hours. A powerful epitope binning analysis software enables easy visualization of data sets and provides a flexible data matrix that can accommodate a variety of cross-blocking formats.

Applications for High Throughput Octet Systems

  • ELISA Conversion

    ELISA Conversion

    Despite its widespread adoption in industry, variability in results, susceptibility to human error, labor intensive workflow, and slow times-to-result remain as big hurdles for users looking to adopt ELISA in high throughput applications. High throughput Octet systems are aptly designed to solve these problems. ELISA assays can be directly transferred onto Octet systems.

    Read Application Note  

  • Epitope Binning

    Epitope Binning

    Epitope binning studies rely on the sequential binding of two antibodies to an antigen, and are performed using dozens of antibody pairs in cross-competition matrices. The Octet system excels at these large-scale studies due to assay speed, throughput, and exceptional reproducibility

    Read Application Note  

  • Protein Contaminant Testing

    Protein Contaminant Testing

    Protein contaminants are a major hurdle to overcome during the production of biopharmaceuticals. The Octet® platform's rapid high throughput protein analysis combined with the anti-CHO HCP and Residual Protein A kits (designed with sensitivity in mind) provide biologics developers with a rapid and easy to use technique for contaminant testing

    Download Technical Note  

Specification & Options of High Throughput Octet Systems: Octet HTX and Octet RED384

Resources of High Throughput Octet Systems: Octet HTX and Octet RED384

Videos and Demos

Automated workflow solutions for the Octet HTX and RED384 systems

Related Products & Services of High Throughput Octet Systems: Octet HTX and Octet RED384

Customer Breakthrough

Mabtech AB uses the Octet RED384 system to help optimize the selection of new antibody producing cells
Mabtech AB uses the Octet RED384 system to help optimize the selection of new antibody producing cells

SUCCESS STORY

Mabtech AB uses the Octet RED384 system to help optimize the selection of new antibody producing cells

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We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.

Ready to get started?

We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.