Axon Patch-Clamp

Systems for whole cell patch-clamp, extracellular, and single-channel recordings

The Axon Instruments® portfolio provides comprehensive solutions for patch-clamping that includes amplifiers, digitizer, software, and accessories. Our best-in-class instruments facilitate the entire range of patch-clamp technique experiments from the smallest single-channel to the largest macroscopic recordings. With the addition of Axon™ pCLAMP™ 11 Software Suite for acquisition, recording and analysis, a truly streamlined workflow is realized.

  • Eliminate line-frequency noise

    The HumSilencer™ feature removes 50/60 hz line-frequency noise on up to four channels in parallel. The function is quickly enabled through a software checkbox.

  • Maximize signal-to-noise ratio

    The Axopatch™ 200B Amplifier offers one of the lowest-noise, single-channel recordings available via an innovative actively cooled headstage with capacitor-feedback technology.

  • Streamline workflows

    pCLAMP Software offers a selection of modules and tools that simplifies setup and enables automation of parameters.


A complete workflow solution for patch-clamp electrophysiology

  • Amplification—amplify your success

    • Control via pCLAMP software maximizes flexibility in setting up and performing different experimental protocols
    • A wide range of amplifiers means we can offer the ideal choice for your application, providing the best possible data
    • Our lowest-noise amplifier/digitizer instruments provide the highest signal resolution, and eliminate 50 or 60 Hz line-frequency noise contamination
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Axon pCLAMP 11 Software

Axon Instruments Patch-Clamp Amplifiers

Axon pCLAMP 11 Software

The Axon™ Digidata® 1550B plus HumSilencer®

  • Digitization—get better data, faster

    • High rate of sampling (500kHz) means a more faithful digitization process, allowing for precise digital reconstruction of the analogue signal due to minimal information loss
    • Eight channels can be sampled and digitized simultaneously, increasing data acquisition speed
    • The HumSilencer option with the Digidata range eliminates of 50 and 60Hz line-frequency noise, making the biological signal clearer without distorting the data
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  • Acquisition — get more flexibility and easier acquisition

    • Enhanced protocol editor in pCLAMP 11 Software allows for longer and more sophisticated protocols to be programmed and reduces protocol setup time
    • Multiple windows can be simultaneously displayed during a Membrane Test protocol, making it easier to patch multiple cells
    • Gap-free mode allows the programming of command and digital outputs in a continuous recording, allowing you to enhance protocol design and trigger actions within the protocol automatically
  • Analysis—discover more while saving time

    • Acquisition and analysis are combined in one package, streamlining the entire process
    • Advanced modules allow action potential and population spike measurements to be made automatically
    • New Batch Analysis feature allows multiple datasets to be analysed using an identical macro; saving time on data analysis and ensuring the exact same analysis is carried out on each dataset
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pCLAMP 11 Software Suite

pCLAMP 11 Software Suite