Patch-clamp analysis software with Clampfit Advanced Analysis Module

The pCLAMP™ Software Suite is an industry-leading patch-clamp electrophysiology data acquisition and analysis program for the control and recording of voltage-clamp, current-clamp, and patch-clamp experiments. The software suite consists of Clampex 11 Software for data acquisition, AxoScope 11 Software for background recording, Clampfit 11 Software for data analysis, and optional Clampfit Advanced Analysis Module for sophisticated and streamlined analysis.

  • Design advanced protocols easily

    Design advanced protocols easily

    The enhanced protocol editor enables up to 50 epochs instead of 10, providing the flexibility to program longer, more sophisticated protocols.

  • Streamline workflows

    Streamline workflows*

    Batch analysis macros enable the analysis of data files in batches and eliminates the need to define parameters for every data set.

  • Analyze faster

    Analyze faster*

    Automated event detection analyzes spontaneous and evoked action potentials and post-synaptic data. Identify events based on a variety of factors.

pCLAMP 11

Features

  • Comprehensive analysis tools

    The software includes a wealth of analysis tools including 24 cursor pairs for regions of interest search, graph plotting tools such as I-V plot and histogram, and more.

  • Improved visualization

    The membrane testwindow displays up to eight channels simultaneously, making it easier to control multiple channels.

  • Enhanced gap-free mode

    A simple continuous "chart-recorder" useful for monitoring single channel events, minis, and other spontaneous activities. Protocol-editor-style epochs and program digital or analog outputs can be executed.

  • Population spike analysis*

    This tool automatically calculates amplitude, area under the curve, half-width, decay and rise time, decay and rise slope, coastline of spike, and paired pulses.

  • Action potential analysis*

    This feature automatically detects and analyzes amplitude, APD90, rise and decay time, rise and decay slope, peak-to-peak frequency and time, and more.

  • Batch analysis*

    Macros for batch analysis eliminates the need to define parameters for every data set. Saved macros can be applied to multiple data sets for automatic analysis.

*Clampfit Advanced Analysis Module only 

Specifications & Options of pCLAMP 11 Software Suite

 

*Supports all previous versions in a model line.
**We only support Professional, Enterprise, and Ultimate editions but not Home edition.

Resources of pCLAMP 11 Software Suite

Videos and Demos

Using Electrophysiology Studies to Accelerate

Using Electrophysiology Studies to Accelerate Mechanistic Study in Reception and Transmission

pCLAMP 11

Enhanced Protocol Editor in pCLAMP 10

Enhanced Protocol Editor in pCLAMP 11

Population Spike Analysis in pCLAMP 11

Population Spike Analysis in pCLAMP 11

Molecular Devices Batch Data Analysis Macros

Batch Data Analysis Macros

Neuronal Action Potential Analysis

Neuronal Action Potential Analysis

Calculate Decay Time Constant, and Perform Curve Fitting Using Axon pCLAMP Software

How to Combine Traces, Calculate Rise or Decay Time Constant, and Perform Curve Fitting Using Axon pCLAMP Software

Create Customized Command Waveforms Using pCLAMP Software

How to Create Customized Command Waveforms Using the pCLAMP Software

Use of Sequencing Keys, User List, and Stimulus File with pCLAMP Software

The Use of Sequencing Keys, User List, and Stimulus File with pCLAMP Software

Synchronizing Electrophysiology and Imaging Solutions with pCLAMP and MetaMorph Software

Synchronizing Electrophysiology and Imaging Solution with Axon pCLAMP and MetaMorph Software

Membrane Test Between Sweeps in Clampex & Analysis of Synaptic Events with Clampfit Data Analysis

Online Statistics, Membrane Test Between Sweeps in Clampex and Analysis of Synaptic Events with the Clampfit™ Data Analysis

Use of Axoporator for Single-cell Electroporation for Transfection and Dye-labeling

Use of the Axoporator 800A for Single-cell Electroporation for Transfection and Dye-labeling

Using Axoclamp 900A for Two-Electrode Voltage-Clamp of Xenopus Oocytes Expressing Ion Channels

Using the Axoclamp 900A for Two-Electrode Voltage-Clamp of Xenopus Oocytes Expressing Ion Channels

Use of Filters in Data Acquisition and the Clampfit Application

Writing Long-Term Potentiation and Depression Protocols and the Use of Filters in Data Acquisition and the Clampfit Application

Resistance Compensated Series

Series Resistance Compensated or Not

Hardware Choices for Optogenetics Considerations for Synchronized Light Patterning

Update and Hardware Choices for Optogenetics Considerations for Synchronized Light Patterning

Effects of Amyloid-Beta Proteins on hSlo1.1, a BK Channel, in Xenopus Oocyte Model

Investigations of the Effects of Amyloid-Beta Proteins on hSlo1.1, a BK Channel, in a Xenopus Oocyte Model

Nanopores-Electronic Tools for Single-Molecule Biophysics and Bio-Nanotechnologies

Nanopores-Electronic Tools for Single-Molecule Biophysics and Bio-Nanotechnologies

Axon Amplifiers and pCLAMP Software-key Features Reviews (Chinese version)

Axon Amplifiers and pCLAMP Software-key Features Reviews (Chinese version)

Using Clampfit in Basic Single Channel Analysis

Basic Single Channel Analysis Using Clampfit

Action Potential Analysis in Clampfit Module

Action Potential Analysis in Clampfit Module

A Walkthrough of Protocol Editor in pCLAMP Data Acquisition Module

A Walkthrough of the Protocol Editor in the pCLAMP Data Acquisition Module

A Walkthrough of Protocol Editor in pCLAMP (Chinese version)

A Walkthrough of Protocol Editor in pCLAMP (Chinese version)

Related Products & Services of pCLAMP 11 Software Suite

Customer Breakthrough

Allegheny College uses Axon Patch-Clamp to Investigate Amyloid Beta Peptide Block Ion Channels in Alzheimer's Disease
Allegheny College uses Axon Patch-Clamp to Investigate Amyloid Beta Peptide Block Ion Channels in Alzheimer's Disease

SUCCESS STORY

Allegheny College uses our Axon patch-clamp instruments to investigate how amyloid beta peptide block ion channels in Alzheimer's disease

Investigating how amyloid beta peptide blocks io channels in Alzheimer's disease

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Ready to get started?

We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.

Maximize flexibility in application workflow and experimental design

Contact our specialist today to discuss how to implement a solution that works for you

Ready to get started?

We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.

Maximize flexibility in application workflow and experimental design

Contact our specialist today to discuss how to implement a solution that works for you