ImageXpress Micro XLS Widefield High-Content Analysis System

The ImageXpress® Widefield system is the ultimate combination of speed and flexibility in a turnkey solution to streamline the research and discovery workflow. It captures research-quality images with the widest range of objective lenses, enabling you to work at the resolution appropriate for your biology, including small organism, cellular or intracellular events. The system’s robust design precisely locates and identifies sub-cellular features, over multi-day time-lapse experiments when required.

Fewer images per well and shorter imaging time with a field of view that is 3x larger than industry standard.

A breadth of applications enabled by objectives ranging from 1x to 100x, 0.05 to 0.95 NA for air and 1.4 NA for oil, capturing a variety of cellular and intra-cellular events.

Accurate stage positioning for capturing high-resolution tiled or stitched images with fully-automated 100 nm resolution voice coil-driven stages, thereby minimizing X-Y stage jitter and ensuring repeatability of extended live-cell experiments.

Up to 5x faster read times while minimizing photobleaching with industry-leading autofocus using a dedicated 690 nm focus laser and ultra-fast sensors.

High-throughput screening captures > 10 million cells/hour in a low-resolution, whole-well, 3 color cell scoring application, or > 1 million cells/hour in a high resolution two-color assay.

Minimized user intervention using automated 5-position filter cube changer, facilitating multiplex assays with up to five filter sets and four objectives for a single experiment.

Modular design allowing for transmitted light, phase contrast, environmental control, fluidics, light source and external filter wheel selection.

Extensive sample compatibility from slides to plates (6- to 1536-well), thin to thick plate bottoms, glass to plastic, transwell, low profile- and low volume-plates.

Integrated automation, 24/7 with 3rd party robotic plate handling system, enabling you to schedule multiple runs.

Resources of ImageXpress Micro XLS Widefield High-Content Analysis System

Videos and Demos

Whole Organism Imaging

Whole Organism Imaging

High-Content Screening for Identifying miRNAs

High-Content Screening for Identifying miRNAs

Identification of Selective Inhibitors of the STAT3 Signaling Pathway

Identification of Selective Inhibitors of the STAT3 Signaling Pathway

Learn How to Change Filter Cubes inside the ImageXpress Micro System

Learn how to change filter cubes inside the ImageXpress Micro System

ImageXpress Micro XLS High Content Imaging Workflow

ImageXpress Micro XLS System high content imaging workflow

Preparing Assays for Genome-wide RNAi Screens

Preparing Assays for Genome-wide RNAi Screens Using High Content Microscopy

Adult Stem Cells Engineered for Delivery of Therapeutic Factors

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies

High-throughput RNA Screening to Identify Host Factors

Using High-throughput RNA Screening to Identify Host Factors That Impact Viral Infection

3D Spheroid Assays Using High-Content Imaging

Setting up 3D Spheroid Assays Using High-Content Imaging

Customer Breakthrough

Gustave Roussy Cancer landing
Gustave Roussy Cancer landing

SUCCESS STORY

Gustave Roussy Cancer Center uses the ImageXpress Widefield Systems to assess mechanisms of cell stress and death in cancer treatment

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Ready to get started?

We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.

Ready to get started?

We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.