ImageXpress Micro XLS Widefield High-Content Analysis System
ImageXpress Micro XLS has been replaced by the ImageXpress Micro 4 High-Content Imaging System
The ImageXpress Micro XLS High-Content Analysis System is a legacy product and has been replaced by the ImageXpress Micro 4 High-Content Imaging System.
The ImageXpress Micro 4 represents the culmination of four generations of imaging expertise. This highly configuralble widefield imager offers greater speed and flexibility, with the option to upgrade to confocal in the future and expand alongside your research.
The following information and resources are provided for your reference only. We will continue to offer support and service for our legacy products. Should you need assistance or would like to discuss your imaging solution, please contact our customer support team.
ImageXpress Micro 4 High-Content Imaging System
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Brochure
Imaging Solutions to Answer Your Biological Questions
Imaging Solutions to Answer Your Biological Questions
Learn about our imaging family and which solution is best suited to answer your biological questions.
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Brochure
ImageXpress Micro Confocal high-content imaging system
ImageXpress Micro Confocal high-content imaging system
The ImageXpress Micro Confocal High-Content Imaging System provides improved quantification for live or fixed cell assays. This versatile imaging system features a unique confocal technology…
Featured applications
3D Cell Models
Development of more complex, biologically relevant, and predictive cell-based assays for…
Cell Counting
The ability to accurately quantitate cell number in multi-well microplates enables a multitude…
Cell Imaging & Analysis
Researchers have several options in methods for imaging cells, from phase-contrast microscopy…
Cell Line Development
Stable cell lines are widely used in a number of important applications including biologics (e.…
Resources of ImageXpress Micro XLS Widefield High-Content Analysis System
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Brochure
Imaging Solutions to Answer Your Biological Questions
Imaging Solutions to Answer Your Biological Questions
Learn about our imaging family and which solution is best suited to answer your biological questions.
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Brochure
ImageXpress Micro Confocal high-content imaging system
ImageXpress Micro Confocal high-content imaging system
The ImageXpress Micro Confocal High-Content Imaging System provides improved quantification for live or fixed cell assays. This versatile imaging system features a unique confocal te…
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Brochure
ImageXpress Micro XLS Widefield High Content Screening System
ImageXpress Micro XLS Widefield High Content Screening System
Explore ImageXpress Micro Widefield High Content Screening System, a combination of speed & flexibility in a turnkey solution to streamline research & workflow.
Blog
Get to know our Field Applications Scientist: Kayla Hill
Get to know our Field Applications Scientist: Kayla Hill
Kayla Hill discusses the latest trends in cellular imaging We recently hosted a webinar with our Field Applications Scientist, Kayla Hill, PhD, who explored high-content analysis…
Customer Breakthrough
Gustave Roussy Cancer Center uses the ImageXpress Widefield Systems to assess mechanisms of cell stress and death in cancer treatment
Gustave Roussy Cancer Center uses the ImageXpress Widefield Systems to assess mechanisms of cell stress and death in cancer treatment
The Kroemer Lab is interested in the molecular mechanisms of cellular stress and death. The mode of cellular stress and death that is evoked during cancer treatment has profound ther…
Scientific Poster
High-Throughput Assays for Characterizing Viability and Morphology of 3D Cancer Spheroid Cultures
High-Throughput Assays for Characterizing Viability and Morphology of 3D Cancer Spheroid Cultures
Three-dimensional (3D) in vitro models span the gap between two-dimensional cell cultures and whole-animal systems. By mimicking features of the in vivo environment and taking advant…
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Customer Breakthrough
University of Sheffield uses ImageXpress Widefield system to run genome-wide screens in Drosophila
University of Sheffield uses ImageXpress Widefield system to run genome-wide screens in Drosophila
Funded by Yorkshire Cancer Research and the UK cancer charity, the Sheffield RNAi Screening Facility was established as the first Drosophila RNAi screening center in the UK. The faci…
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Customer Breakthrough
Iowa State University uses the ImageXpress Widefield system to develop strategies to rescue and repair of damaged nervous systems
Iowa State University uses the ImageXpress Widefield system to develop strategies to rescue and repair of damaged nervous systems
Research in the Sakaguchi Lab at Iowa State University focuses on experimental strategies for the rescue and repair of the damaged nervous system using stem cell approaches. Specific…
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Customer Breakthrough
Neuro-Sys uses the ImageXpress Widefield System to advance understanding of neurodegenerative disease
Neuro-Sys uses the ImageXpress Widefield System to advance understanding of neurodegenerative disease
Neuro-Sys is an innovative, private contract research organization (CRO), drug development and drug discovery company in France which focuses mainly on neurodegenerative diseases, su…
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Customer Breakthrough
University of Zurich uses the ImageXpress Widefield System to investigate host pathogen interactions
University of Zurich uses the ImageXpress Widefield System to investigate host pathogen interactions
At the University of Zurich, researchers are interested in late events that occur in human cells infected by replicating pathogens such as viruses. These events typically involve she…
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Scientific Poster
Phenotypic Assessment of Toxicity Using a Human Hepatocyte Co-Culture Model
Phenotypic Assessment of Toxicity Using a Human Hepatocyte Co-Culture Model
Development of predictive in vitro assays for early toxicity evaluation is extremely important for improving the drug development process and reducing drug attrition rates during cli…
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Customer Breakthrough
Vanderbilt Institute of Chemical Biology uses the ImageXpress Widefield system for biological screening and drug discovery
Vanderbilt Institute of Chemical Biology uses the ImageXpress Widefield system for biological screening and drug discovery
The High Throughput Screening (HTS) facility at the Vanderbilt Institute of Chemical Biology is a highly dynamic environment that utilizes industry standard practices and novel techn…
Application Note
Homogeneous Antibody Binding Assay with High Content Imaging
Homogeneous Antibody Binding Assay with High Content Imaging
The development of homogeneous antibody binding assays has increased the efficiency for high throughput, high content analysis of cell and bead assays. These no wash, fluorometric…
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Application Note
3D Imaging of Cancer Cell Spheroids
3D Imaging of Cancer Cell Spheroids
Many cancer cell lines will form spheroids if cultured on a favorable three dimensional (3D) matrix. These spheroids are believed to represent tumor physiology more closely than cells…
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Application Note
Live cell kinetics assay utilizing the ImageXpress Micro System
Live cell kinetics assay utilizing the ImageXpress Micro System
The ImageXpress® Micro Confocal/ XLS Widefield High-Content Imaging System from Molecular Devices includes optional Fluidics and Environmental Control modules, enabling single-channel…
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Application Note
Assaying cardiotoxicity with ImageXpress high-content screening systems
Assaying cardiotoxicity with ImageXpress high-content screening systems
The discovery and development of novel drugs is a difficult and expensive process due to lack of tools and techniques to accurately reproduce the human physiological response in the…
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Application Note
Visualize subcellular vesicles to quantitate autophagy in neuronal cells
Visualize subcellular vesicles to quantitate autophagy in neuronal cells
Autophagy is an intracellular catabolic process that sequesters and degrades proteins and organelles that have either been recognized as faulty or are simply no longer needed by the…
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Application Note
High-throughput imaging assays using zebrafish, a model organism for human disease
High-throughput imaging assays using zebrafish, a model organism for human disease
Recently, zebrafish-based screening has gained favor as an alternative to mammalian screening due to cost, throughput and reduced ethical concerns. Zebrafish are a useful model for…
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Application Note
Apoptosis detection using EarlyTox Caspase-3/7-D NucView 488 Assay Kit on ImageXpress Micro systems
Apoptosis detection using EarlyTox Caspase-3/7-D NucView 488 Assay Kit on ImageXpress Micro systems
Apoptosis is an important mechanism signaling programmed death of cells in normal processes such as embryonic development, as well as in diseases including cancer and neurodegenerative…
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Application Note
High-content screening of neuronal toxicity using iPSC-derived human neurons
High-content screening of neuronal toxicity using iPSC-derived human neurons
The nervous system is sensitive to the toxic effects of many chemical compounds, environmental agents and certain naturally occurring substances. Neurotoxicity can cause temporary or…
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Application Note
Intelligent time-lapse imaging to enhance live cell assay development
Intelligent time-lapse imaging to enhance live cell assay development
The ability to monitor responses in living cells over a specific period of time offers cell biologists several key advantages for assay development. For routine cellbased screening,…
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Application Note
Multiplexed high-content hepatotoxicity assays using iPSC-derived hepatocytes
Multiplexed high-content hepatotoxicity assays using iPSC-derived hepatocytes
Drug-induced hepatotoxicity is an important cause for liver injury and acute liver failure. Thus highly predictive assays for safety and efficacy testing are crucial for improving drug…
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Scientific Poster
Predictive Assays for High Throughput Assessment of Cardiac Toxicity and Drug Safety
Predictive Assays for High Throughput Assessment of Cardiac Toxicity and Drug Safety
Read more about cell based assays for measuring the impact of pharmacological compounds on the rate of beating cardiomyocytes with different assay platforms.
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Scientific Poster
Meeting Ultra‐High Throughput Imaging Challenges: Low Resolution, 1536 Well Plates, Homogeneous Assays
Meeting Ultra‐High Throughput Imaging Challenges: Low Resolution, 1536 Well Plates, Homogeneous Assays
Explore solutions for scale-up challenges, such as imaging 1536‐well plates, obtaining useful imaging data from homogeneous assays, & shortening time to results.
Hybridoma Workflow
Whole Organism Imaging
High-Content Screening for Identifying miRNAs
Identification of Selective Inhibitors of the STAT3 Signaling Pathway
Learn how to change filter cubes inside the ImageXpress Micro System
ImageXpress Micro XLS System high content imaging workflow
Preparing Assays for Genome-wide RNAi Screens Using High Content Microscopy
High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies
Using High-throughput RNA Screening to Identify Host Factors That Impact Viral Infection
Setting up 3D Spheroid Assays Using High-Content Imaging
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Provides robust, quantitative results from complex biological images and datasets
Gustave Roussy Cancer Center uses the ImageXpress Widefield Systems to assess mechanisms of cell stress and death in cancer treatment
Case studySENS Research Foundation uses the ImageXpress Micro Widefield system to speed up cancer research 20 times
Case studyUniversity of Zurich uses the ImageXpress Widefield System to investigate host pathogen interactions
Case studyVanderbilt Institute of Chemical Biology uses the ImageXpress Widefield system for biological screening and drug discovery
Case study