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Explore our fully-integrated, automated workflow solutions for cell and biochemical assays

 

Plate-based assays form the cornerstone of many laboratory research programs. Whether you are performing biochemical assays such as ELISA, DNA/RNA quantitation, MTT cytotoxicity, or binding/affinity or cell-based assays such as CRISPR, viral titer, protein expression, bacterial growth, or cell signaling, Molecular Devices microplate readers have empowered life science researchers to advance discovery and produce high quality, reliable data.

As timelines become compressed and the amount of data required for IND submissions and publications increases, laboratories are increasingly pressed to do more with less. The introduction of automated workcells can help relieve this burden by allowing researchers to optimize their time in the lab and obtain data more efficiently. Additionally, automated data collection and data tracking reduce human error, assuring that the data is of a higher quality.

 

 

Scalable, automated plate-based assay workcells

We work with you to build flexible, scalable, future-proof workcells that will meet the needs of your current workflow, as well as give you room to grow and expand in the future. We bring decades worth of consultative expertise to the table to help you design and implement workcells that incorporate industry-leading technology to achieve your goals. However, we recognize that your needs may change and evolve over time, therefore, we will continue to provide robust support and development to make sure your system continues to meet your needs.

 

Automated plate loading

Dip your toes into the water of laboratory automation with this entry-level system. Perform microplate-based assays on a large number of plates without having to manually feed them into your microplate reader. Load up the plates you need run and walk away while the robotic arm delivers them to the instruments to be read.

  • Microplate reader: SpectraMax® iD5 Multi-Mode Microplate Reader
  • Microplate washer: AquaMax® 4000 Microplate Washer
  • Robot: Peak Robotics S-LAB Plate Handler
  • Plate storage: Plate hotels – 40 microtiter plates
  • Integration software: Peak Robotics S-LAB Software
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Future proof automated plate loading

Ensure that your system can scale as your workflow expands by setting yourself up with a more sophisticated robotic arm. This system allows you to manually load assay plates into ambient hotels so that the robot arm can deliver them to the microplate reader when needed. A collaborative, four-axis robotic arm allows for the easy addition of instrumentation should your workflow require it in the future. (Instrument additions could include incubators, cellular imagers, single-cell sorters, centrifugation, and more) .

  • Plate reader: SpectraMax iD5 Multi-Mode Microplate Reader
  • Plate washer: AquaMax 4000 Microplate Washer
  • Robot: PreciseFlex 400 Sample Handler
  • Plate storage: Plate Hotels – 40 microtiter plates
  • Integration software: Genera scheduling software
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  • Request Quote

 

Automated plate handling, loading, and incubation

Eliminate the need to manually load plates onto the workcell and keep your plates in an environmentally regulated location with the addition of an automated incubator. Simply load your plates into the incubator, and the robot will deliver them to the plate reader at the designated time.

  • Plate reader: SpectraMax iD5 Multi-Mode Microplate Reader
  • Plate washer: AquaMax 4000 Microplate Washer
  • Robot: PreciseFlex 400 Sample Handler
  • Plate storage: Plate Hotels – 40 microtiter plates
  • Integration software: Genera scheduling software
  • Incubation: LiCONiC STX44 Automated CO2 Incubator
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  • Request Quote

 

Plate loading, automated plate handling, incubation, and liquid handling

Enjoy increased flexibility and increased walkaway time with the addition of a liquid handler. An automated liquid handler allows the workcell to perform simple tasks, such as media changes or reagent additions, at the times you designate. This will enable you to conduct many assays with great precision and minimal manual intervention.

  • Plate reader: SpectraMax iD5 Multi-Mode Microplate Reader
  • Plate washer: AquaMax 4000 Microplate Washer
  • Incubation: LiCONiC STX44 Automated CO2 Incubator
  • Liquid handler: Microlab STARlet Robot Liquid Handler
  •  

  • Request Quote

 

Fully automated workflow

Harness the full potential of laboratory automation with maximum walkaway time. No further manual intervention is required once plates are loaded into the automated incubator. Plates will be moved automatically from the incubator into the workcell so that assays and treatments can be performed at designated times.

  • Plate reader: SpectraMax iD5 Multi-Mode Microplate Reader
  • Plate washer: AquaMax 4000 Microplate Washer
  • Robot: PreciseFlex 400 Sample Handler
  • Plate storage: Plate hotels – 40 microtiter plates
  • Integration software: Genera scheduling software
  • Incubation: LiCONiC STX44 Automated CO2 Incubator
  • Liquid handler: Microlab STAR Automated Liquid Handler
  •  

  • Request Quote

 

Application highlight: High-throughput ELISA workflow

 

ELISA (Enzyme-linked Immunosorbent Assay) is one of the most popular quantitative methods to detect a target antigen such as toxin or foreign substance within a sample. The assay is easy to set up and the range of potential analytes is vast, but the assay procedure is time consuming and labor intensive.

Laboratory automation workflows can help with providing walkaway time, increasing throughput, effectiveness and efficiency of the assay procedure, and reproducibility. 

  • Biomek i7 automated liquid handler executes dispensing reagent or samples via multichannel head.
  • Using an automated heat sealer, a sealing film will be placed on the assay plate to prevent evaporation during incubation.
  • The incubation is done at room temperature in a LiCONiC LPX44, that can store to 44 microplates and while shaking them during the incubation period.
  • After incubation, the assay plate is transferred to the seal-peeler to remove the seal from the assay plate and transferred to washing.
  • Aspirating and dispensing of wash buffer can occur simultaneously in all wells via AquaMax® 4000 Microplate Washer with a 96- or 384-well head.
  • Once the assay runs its course, the final absorbance readout will take place on a SpectraMax® iD5 Multi-Mode Microplate Reader.
  • SoftMax® Pro Software will automatically generate a standard curve and calculate target antigen concentration in unknown samples.

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