ImageXpress Pico Automated Cell Imaging System
Cellular imaging and analysis system that enables you to go from sample to results in minutes
Digital microscopy with automated brightfield and fluorescence imaging
The ImageXpress® Pico Automated Cell Imaging System is more than a digital microscope, combining high-resolution imaging with powerful analysis. Whether running fluorescence imaging or brightfield assays, the automated imager features a comprehensive portfolio of preconfigured protocols for cell-based assays to shorten the learning curve, so you can start running experiments quickly.
-
Get started quickly
Streamline digital microscopy with the icon-driven, user-friendly CellReporterXpress™ software to minimize setup and shorten training time.
-
Do more than cell counting
Expand your assay capabilities with over 25 preconfigured templates optimized for cell-based experiments including apoptosis, mitochondrial evaluation, 3D cell models, live cell/time lapse, and neurite tracing.
-
Image economically
Alleviate the hassle of going to the core lab to run your samples. The system’s lab-friendly price affords the convenience of automated digital microscopy in every lab.
ImageXpress Pico Automated Cell Imaging System-Interactive Demo
Features
-
Multiple imaging modes
The ImageXpress Pico system offers objectives ranging from 4x to 63x and can operate in colorimetric, brightfield, or fluorescence imaging modes.
-
Preconfigured analysis protocols
Preconfigured analysis protocols ranging from cell counting to sophisticated neurite tracing analysis removes the guess work from optimizing parameters.
-
Plate-to-individual cell view
Data can be visualized at multiple levels from plate overview to individual cells. The cell click-to-find tool also makes it easy to automatically locate cells that match specific criteria.
-
Z-stack acquisition
Z-stack acquisition enables the generation of sharper images and more accurate segmentation. A series of images acquired at different focal points captures more details than with an individual slice.
-
Advanced slide-imaging workflow
Time and data storage can be saved by scanning an overview image of a whole slide; then, high resolution scans acquire only selected regions of interest.
-
Environmental control
Multi-day, time lapse, and live cell assays can be run on the system. The software provides real-time monitoring of environmental state, ensuring optimal assay conditions. Product option includes humidity, CO2, and O2 control.
-
Product Brochure
ImageXpress Pico Automated Cell Imaging System
ImageXpress Pico Automated Cell Imaging System
The ImageXpress® Pico system does more than imaging—it offers unparalleled analysis capabilities that simplifies image analysis for cell-based assays.
-
Scientific Poster
Cytotoxic analysis using iPSC-derived stem cell models
Cytotoxic analysis using iPSC-derived stem cell models
Automate complex cell-based assays with multi-parametric readouts while maintaining high data quality and precision.
Applications of ImageXpress Pico Automated Cell Imaging System
-
Neurite Outgrowth / Neurite Tracing
Neurons create connections via extensions of their cellular body called processes. This biological phenomenon is referred to as neurite outgrowth. Understanding the signaling mechanisms driving neurite outgrowth provides valuable insight into neurotoxic responses, compound screening, and for interpreting factors influencing neural regeneration. Using the ImageXpress Micro system in combination with MetaXpress Image Analysis Software automated neurite outgrowth imaging and analysis is possible for slide or microplate-based cellular assays.
-
Apoptosis Analysis
Apoptosis is a process of programmed cell death important to a number of biological processes including embryonic development and normal tissue maintenance. Disruption in the regulation of apoptosis has been implicated in various diseases including cancer. Biochemical events lead to characteristic changes in cell morphology such as cell shrinkage, nuclear fragmentation, chromatin condensation, and mRNA decay, and ultimately cell death. Apoptosis can be initiated via the intrinsic or extrinsic pathways, and both pathways induce cell death by activating caspase enzymes
-
Cell Counting
Cell counting is fundamental and critical to numerous biological experiments. Assays such as drug compound toxicity, cell proliferation, and inhibition of cell division have a need to assess the number or density of cells in a well. Automated imaging can greatly speed up the cell counting process while reducing manual labor and human errors. Cells can be counted using a variety of methods, such as label-free cell counting under transmitted light or detection of nuclear dye with fluorescent imaging.
Resources of ImageXpress Pico Automated Cell Imaging System
-
Product Brochure
ImageXpress Pico Automated Cell Imaging System
ImageXpress Pico Automated Cell Imaging System
The ImageXpress® Pico system does more than imaging—it offers unparalleled analysis capabilities that simplifies image analysis for cell-based assays.
-
Scientific Poster
Cytotoxic analysis using iPSC-derived stem cell models
Cytotoxic analysis using iPSC-derived stem cell models
Automate complex cell-based assays with multi-parametric readouts while maintaining high data quality and precision.
-
Scientific Poster
Phenotypic cell-based assays with a new automated imaging system and cell analysis software
Phenotypic cell-based assays with a new automated imaging system and cell analysis software
There is a great need to automate complex cell-based assays with multi-parametric read-outs while maintaining high data quality and precision. A compact, automated imaging system was us…
Application Note
Monitor cell proliferation and cell cycle in real time
Monitor cell proliferation and cell cycle in real time
There is an increased need to expand the variety and complexity of cell-based assays for biological research and drug discovery. Live-cell assays allow monitoring of cell responses in…
-
Application Note
Evaluate anti-inflammatory compounds using a multiparametric THP-1 cell-based assay
Evaluate anti-inflammatory compounds using a multiparametric THP-1 cell-based assay
Macrophages originate from blood monocytes that leave the circulation and penetrate various tissues where they differentiate into macrophages.
-
Application Note
Count cells with or without fluorescent labels using automated imaging
Count cells with or without fluorescent labels using automated imaging
The ability to accurately quantitate cell number in multi-well microplates enables a multitude of biological applications that study cell health or proliferation.
-
Application Note
Measure cell migration using discontinuous time-lapse imaging of live cells
Measure cell migration using discontinuous time-lapse imaging of live cells
Cell migration is an essential process required for many biological events including embryonic development, wound healing, cancer metastasis, and immunological responses.
-
Application Note
Multiplexed automated imaging assay for cardiotoxic compounds using the ImageXpress Pico system
Multiplexed automated imaging assay for cardiotoxic compounds using the ImageXpress Pico system
Develop functional and morphological readouts for testing effects of different compounds in multi-parametric assays using iPSC-derived cardiomyocytes
-
Application Note
Identify compound-specific effects on neurite outgrowth using ImageXpress Pico system
Identify compound-specific effects on neurite outgrowth using ImageXpress Pico system
Evaluate compound-specific effects on neurite outgrowth using automated imaging
-
Application Note
Detection of autophagy using ImageXpress Pico System
Detection of autophagy using ImageXpress Pico System
Detect and quantify compound effects on the process of autophagy on the ImageXpress Pico system. The PC12 human neuroblastoma cell line was used as a model for assay development.
-
Application Note
Multi-parametric assessment of cell phenotypes using ImageXpress Pico Automated Cell Imaging System
Multi-parametric assessment of cell phenotypes using ImageXpress Pico Automated Cell Imaging System
Automated cellular imaging is an efficient method for analyzing compound effects on cell phenotypes including morphology, viability, and marker expression.
-
Application Note
Evaluation of mitochondrial integrity and mitochondria membrane potential using automated cell imaging and analysis
Evaluation of mitochondrial integrity and mitochondria membrane potential using automated cell imaging and analysis
Mitochondrial function, a key indicator of cell health, can be assessed by monitoring changes in mitochondrial membrane potential (MMP)1,2.
-
Application Note
Cytotoxicity assessment using automated cell imaging and live/dead assays
Cytotoxicity assessment using automated cell imaging and live/dead assays
Live/dead assays are utilized in a wide variety of research applications including investigation of cytotoxic effects of various compounds, treatments, or changes in gene expression.
-
Application Note
Analysis of apoptosis using automated cell imaging
Analysis of apoptosis using automated cell imaging
Apoptosis is a process of programmed cell death that occurs in multicellular organisms.1,2 Biochemical events lead to characteristic changes in cell morphology and cell death.
eBook
Quantitate Neuron Potential
Quantitate Neuron Potential
Gain valuable insights into neurobiology, from evaluation of ion channels to analysis of 3D neuron organoids.
-
eBook
Cellular Imaging Insights
Cellular Imaging Insights
Gain insights and expedite studies for 2D and 3D cellular structures using automated cellular imaging.
Flyer
Assay kits for the ImageXpress Pico system
Assay kits for the ImageXpress Pico system
These assay kits are a family of fluorescence-based reagents for the assessment of cell viability, cell proliferation, and apoptosis events using mammalian cells. The kits employ a no-w…
-
Flyer
ImageXpress Pico Automated Cell Imaging System
ImageXpress Pico Automated Cell Imaging System
Replace tedious manual microscope manipulations with the fully automated ImageXpress® Pico Automated Cell Imaging System. Simply place samples into the system and follow the icon-driven…
-
Product Brochure
Imaging Solutions to Answer Your Biological Questions
Imaging Solutions to Answer Your Biological Questions
Learn about our imaging family and which solution is best suited to answer your biological questions.
-
Scientific Poster
Live-cell assays measuring complex compound effects in real time
Live-cell assays measuring complex compound effects in real time
Monitor cell responses in real time to acquire important qunatitative insights
-
Scientific Poster
A novel high-throughput solution for screening drugs with a light-crosslinked VersaGel 3D tumor culture model and automated high-content imaging
A novel high-throughput solution for screening drugs with a light-crosslinked VersaGel 3D tumor culture model and automated high-content imaging
Screen models that mimic in vivo tumor microenvironment using novel 3D cell culture platform, VersaGel and Symphony
-
Scientific Poster
Measure cell migration using automated cell imaging and analysis
Measure cell migration using automated cell imaging and analysis
Effectively image and analyze cell migration using a scratch assay or a dissolvable biocompatible gel
-
Scientific Poster
Multiplexed automated imaging assays for compound testing using iPSC-derived cell models
Multiplexed automated imaging assays for compound testing using iPSC-derived cell models
Develop functional and morphological readouts for testing effects of different compounds in a multi-parametric assay format
-
Scientific Poster
Cell migration analysis using automated cell imaging
Cell migration analysis using automated cell imaging
Effectively image and analyze cell migration using a dissolvable biocompatible gel.
Videos and Demos
A Product Manager's Tour of the ImageXpress Pico
Configuring environmental control settings on the ImageXpress Pico
How to perform a z-stack image acquisition using CellReporterXpress
Cellular images to results in minutes with automated imaging
Setting up acquisition and analysis on the ImageXpress Pico
Transmitted light cell scoring on the ImageXpress Pico
Reviewing completed experiments on the ImageXpress Pico
ImageXpress Pico Automated Cell Imaging System-Interactive Demo
ImageXpress Pico Automated Cell Imaging System
Related Products & Services of ImageXpress Pico Automated Cell Imaging System
Featured Applications
Apoptosis Analysis
Apoptosis is a process of programmed cell death important to a number of biological processes…
Read More
Cell Counting
Cell counting is fundamental and critical to numerous biological experiments. Assays such as drug…
Read More
Neurite Outgrowth / Neurite Tracing
Neurons create connections via extensions of their cellular body called processes. This biological…
Read MoreCustomer Breakthrough
SUCCESS STORY
MIMETAS uses the ImageXpress Pico and ImageXpress Micro Confocal systems to develop tissue models for their OrganoPlates®
A unique 3D organ-on-a-chip platform
Ready to get started?
We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.