Automated fluorescence imaging that’s easier than digital microscopy

The ImageXpress® Pico Automated Cell Imaging System combines high-resolution imaging and powerful analysis, with a streamlined workflow. It includes CellReporterXpress® software for acquisition and analysis, and features a comprehensive portfolio of preconfigured protocols. The automated setup of analysis parameters shortens the learning curve, so you can start running experiments quickly. If you’re in the market for fluorescence imaging or digital microscopy, the ease and affordability of an automated imager is now within reach.

  • Get started quickly

    Get started quickly

    With the approachable, icon-driven CellReporterXpress software, everyone can use the ImageXpress Pico system with minimal training to capture and analyze your first image.

  • Do more than cell counting

    Do more than cell counting

    Expand your assays beyond cell counting with preconfigured templates for many commonly used cell imaging and analysis protocols such as apoptosis and detection of mitochondria.

  • Cost Effective

    Image economically

    Alleviate the hassle of going to the core lab to run your samples. The system’s lab-friendly price affords the convenience of automated imaging and analysis on your lab bench.

ImageXpress Pico Automated Cell Imaging System-Interactive Demo

Features

  • Multiple imaging modes

    The ImageXpress Pico system provides user- and software-selectable objectives ranging from 4X to 63X, fluorescence imaging, live cell imaging, and brightfield imaging modes.

  • Predefined cell imaging protocols

    The system offers preconfigured cell imaging protocols ranging from simple cell count to sophisticated neurite tracing analysis, removing the guesswork from optimizing parameters.

  • Plate-to-individual cell view

    Data can be visualized at multiple levels from plate overviews to individual cells. Images are clickable to locate cells that match specific criteria.

  • Integrated data visualization tools

    Liberate your lab from tedious digital microscopy, the software transforms images into data on the fly. Scatter plots, videos, and more can be generated automatically with just a few clicks.

  • Advanced slide scanning workflow

    Whole slide scanning, for the determination of regions of interest, is quick and easy. Acquires higher resolution scans of only the select regions, saving time and data storage.

  • Temperature control

    Temperature control up to 40C is standard on every ImageXpress Pico system, making live cell imaging a possibility.

Applications of ImageXpress Pico Automated Cell Imaging System

  • Neurite Outgrowth / Neurite Tracing

    Neurite Outgrowth / Neurite Tracing

    Neurons create connections via extensions of their cellular body called processes. This biological phenomenon is referred to as neurite outgrowth. Understanding the signaling mechanisms driving neurite outgrowth provides valuable insight into neurotoxic responses, compound screening, and for interpreting factors influencing neural regeneration. Using the ImageXpress Micro system in combination with MetaXpress Image Analysis Software automated neurite outgrowth imaging and analysis is possible for slide or microplate-based cellular assays.

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  • Apoptosis Analysis

    Apoptosis Analysis

    Apoptosis is a process of programmed cell death important to a number of biological processes including embryonic development and normal tissue maintenance. Disruption in the regulation of apoptosis has been implicated in various diseases including cancer. Biochemical events lead to characteristic changes in cell morphology such as cell shrinkage, nuclear fragmentation, chromatin condensation, and mRNA decay, and ultimately cell death. Apoptosis can be initiated via the intrinsic or extrinsic pathways, and both pathways induce cell death by activating caspase enzymes

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  • Cell Proliferation

    Cell Counting

    Cell counting is fundamental and critical to numerous biological experiments. Assays such as drug compound toxicity, cell proliferation, and inhibition of cell division have a need to assess the number or density of cells in a well. Automated imaging can greatly speed up the cell counting process while reducing manual labor and human errors. Cells can be counted using a variety of methods, such as label-free cell counting under transmitted light or detection of nuclear dye with fluorescent imaging.

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Specifications of ImageXpress Pico Automated Cell Imaging System

Resources of ImageXpress Pico Automated Cell Imaging System

Videos and Demos

Setting up acquisition and analysis on the ImageXpress Pico

Transmitted light cell scoring on the ImageXpress Pico

Reviewing completed experiments on the ImageXpress Pico

ImageXpress Pico Automated Cell Imaging System-Interactive Demo

ImageXpress Pico Automated Cell Imaging System

ImageXpress Pico Automated Cell Imaging System

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Ready to get started?

We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.

Ready to get started?

We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.