Stem Cell Research

Stem Cell Research

Stem cells models offer scientists the benefit of a more biologically relevant system. The FLIPR Tetra High-Throughput Cellular Screening System and imaging systems such as ImageXpress Micro Confocal and ImageXpress Micro 4 enable data acquisition and analysis in high-throughput and high-content environments.

Stem cells provide researchers with new opportunities to study targets and pathways that are more relevant to disease processes. They offer a more realistic model to identify and confirm new drug targets and generate pharmacology and toxicology data earlier, with stronger translation to the clinical setting. Additionally, the application of stem cells in drug development creates a new path to personalized medicine, while at the same time reducing, or even potentially replacing, animal testing. Induced pluripotent stem cell-derived (iPSC-derived) cells enable researchers to study primary cells without the limitations traditionally encountered in obtaining such cells.

Tools used in Stem Cell Research

  • Cardiomyocytes

    Cardiomyocytes

    Stem cells differentiated into cardiomyocytes are used to screen early for potential toxicological effects of drugs, thus helping to avoid investment in development of drugs which will fail in clinical trials due to cardiac toxicity.

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  • Stem Cell Hepatocytes

    Hepatocytes

    Stem cells differentiated into hepatocytes, or liver cells, can be used to predict liver toxicity by drug candidates.

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  • Stem Cell Hematopoietic

    Hematopoietic

    Stem cells differentiated into hematopoietic progenitors (blood-forming stem cells) are important for both cell therapy and drug development. They can be used to study various blood disorders, such as leukemia or immune system disorders.

  • Stem Cell Neurons

    Neurons

    Stem cells differentiated into neurons are often used in drug discovery to study central nervous system (CNS) diseases such as Alzheimer's, schizophrenia, and anxiety. These neurons can also be used in toxicological assays to help predict drug safety and efficacy.

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  • Embryonic Stem Cells

    Embryonic Stem Cells

    Embryonic stem cells (ES) are derived from embryos and are considered pluripotent, meaning able to differentiate into any cell type. There are currently two main cell types, mouse ES cells and human ES cells.

Resources of Stem Cell Research

Videos and Demos

Multi-parameter in vitro assessment of compound effects on cardiomyocyte physiology using induced pluripotent stem cells

Human iPS Cell-derived Neurons

Human iPS Cell-derived Neurons: A New Physiologically Relevant Model for Drug Discovery Applications for High-Content Screening of Neurotoxicity

Live Cell Imaging of Co-Cultured Stem Cells

Live Cell Imaging of Co-Cultured Stem Cells

Time-Lapse Cell Migration Assay of Stem Cells

Time-Lapse Cell Migration Assay of Stem Cells

Mouse Genetically Modified Stem Cells via Transmitted Light and Fluorescence Imaging

Mouse Genetically-Modified Stem Cells via Transmitted Light and Fluorescence Imaging

Adult Stem Cells Engineered for Delivery of Therapeutic Factors

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies

Related Products & Services of Stem Cell Research

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