Institute of Atomic and Molecular Sciences uses MetaMorph software to study proteins at the transition zone of primary cilia

Academia Sinica, Institute of Atomic and Molecular Sciences

Jung-Chi Liao, PhD, Associate Research Fellow

MetaMorph Microscopy Automation and Image Analysis Software

The Challenge

Dr. Jung-Chi Liao’s lab at Academia Sinica in Taiwan focuses on understanding the structure and function of proteins at the base of primary cilia in mammalian cells. Specifically, they aim to reveal the molecular architecture of the ciliary transition zone and transition fibers.

Institute of Atomic and Molecular Sciences uses MetaMorph Software

The Solution

They use MetaMorph® Software with super-resolution image processing to perform two-color fluorescent imaging and have determined the relative positions of proteins at the ciliary base.

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