BioAssemblyBot 400: more than a bioprinter
Intelligent, precise, and scalable automation solution for 3D biology
Automated high-content screening solution with BAB’s 6-axis robotic arm for optimized 3D tissue and organoid workflow
BioAssemblyBot® 400 (BAB400) by Advanced Solutions is an intelligent robot used by life scientists to build 3D model systems with increased throughput and precision, alleviating common concerns associated with manual workflows. As part of an optimized automation workflow that includes ImageXpress® Confocal HT.ai High-Content Imaging System and IN Carta® Image Analysis Software, the BAB’s 6-axis robotic arm utilizes a wide range of interchangeable fabrication tools to reliability reproduce 3D tissues and organoids.
Features
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Extend human ability
The precision of the BAB400’s six-axis robotic arm exceeds human dexterity to bioprint, pick up biology, and complete complex assays while reducing human error, variability, and cost.
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Automate with BioApps™
The user-friendly interface allows you to use existing protocols or customize your own.
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Can I have a hand?
BAB swaps "hands" giving users the ability to 3D bioprint while controlling temperature, pressure, UV exposure, and more with the ever-growing catalog of tools.
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Load in materials and go
Add in your biomaterials and press “go.” BAB will automate countless processes, including passaging cells, bioprinting, organoid dispensing, and more. Once these processes are complete, the BAB will notify you that the work is completed.
Expandable and designed for modern biology and drug discovery labs.
Produce and maintain living tissues, organoids, and spheroids more consistently than ever before. Then analyze them without ever touching the well plate. BAB400 integrates seamlessly with the ImageXpress Confocal HT.ai to round out your integrated organoid workflow with automated passaging, cell culture monitoring, suspension dispensing, and 3D bioprinting of tissues and organoids.
ImageXpress Confocal HT.ai High-Content Imaging System
Powerful multi-laser light sources, a deep tissue penetrating confocal disk module, water immersion objectives and modern machine learning analysis software
- Ideal for highly-complex cell-based and 3D assays
- Seven-channel high-intensity lasers generating brighter images with higher signal-to-background
- Spinning confocal disk technology for deeper tissue penetration, resulting in sharper images with improved resolution
- Water immersion objectives offering quadruple the signal at lower exposure times for greater sensitivity and image clarity without sacrificing speed
- View product
IN Carta Image Analysis Software
Modern machine learning, high-content image analysis software
Powerful analytics combined with an intuitive user interface simplify workflows for image analysis and phenotypic profiling. Advanced features provide the functionality you need to analyze data in 2D, 3D, and 4D - at scale - and deliver real-time insights without the need for complex pre- or post- processing operations. Improve specificity of your image analysis workflows by utilizing the SINAP deep-learning module and see for yourself that Segmentation Is Not A Problem. Put machine learning to work for you and perform complex phenotypic analysis within a user-friendly Phenoglyphs module.
Applications for BioAssemblyBot 400
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3D Cell Models
3D cell cultures offer the advantage of closely recapitulating aspects of human tissues including the architecture, cell organization, cell-cell and cell-matrix interactions, and more physiologically-relevant diffusion characteristics. Utilization of 3D cellular assays adds value to research and screening campaigns, spanning the translational gap between 2D cell cultures and whole-animal models. By reproducing important parameters of the in vivo environment, 3D models can provide unique insight into the behavior of stem cells and developing tissues in vitro.
Drug Discovery and Development
For every drug that makes it to the finish line, another nine don’t succeed. This alarming failure rate can be traced to reliance on 2D cell cultures that don’t closely mimic complex human biology, often leading to inaccurate predictions of a drug’s potential and extended drug development timelines.
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Lab Automation for High-content Screening
Our automated, high-content screening (HCS) workcell provides an end-to-end solution that helps standardize live 2D/3D cellular development process with cell culture, treatment, and incubation, through to imaging, analysis, and data processing, delivering consistent, unbiased, and biologically-relevant results at scale.
Organoid Innovation Center
Our lab automation solutions include scientists and engineers who can customize our instruments, as well as automate entire workflows to meet the specific needs of your assay, method, or protocol. From incubators, liquid handlers, and robotics to customized software and hardware—and with over 35 years of experience in the life science industry—you can count on us to deliver quality products and provide worldwide support.
Learn more about how robotics-driven automation workcells and AI-based image analysis can help you develop an efficient, end-to-end workflow for your organoid development process.
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Organoid Research
Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that are designed to closely mimic the complex structure and functionality of human organs like the lung, liver or brain. Organoids typically consist of a co-culture of cells which demonstrate a high order of self-assembly to allow for an even better representation of complex in vivo cell responses and interactions, as compared to traditional 2D cell cultures.
Toxicology
Toxicology is the study of adverse effects of natural or man-made chemicals on living organism. It is a growing concern in our world today as we are exposed to more and more chemicals, both in our environment and in the products we use.
Resources of BioAssemblyBot 400: more than a bioprinter
Publications
Bioprinting Automation for Drug Discovery to Be Developed by Molecular Devices and Advanced Solutions
Bioprinting Automation for Drug Discovery to Be Developed by Molecular Devices and Advanced Solutions
3DPrint.com, the leading source for actionable intelligence related to 3D printing technology and the larger AM industry, covers our collaboration…
News
Molecular Devices and Advanced Solutions Life Sciences collaborate to develop 3D Biology Automation Technologies for Drug Discovery
Molecular Devices and Advanced Solutions Life Sciences collaborate to develop 3D Biology Automation Technologies for Drug Discovery
Turnkey platform integrates flexible robotic automation with high-content imaging of complex 3D cellular models, enabling high-volume organoid screening SAN JOSE, Calif., Jan. 4, 2023…
Brochure
BioAssemblyBot 400 (BAB400): more than a bioprinter
BioAssemblyBot 400 (BAB400): more than a bioprinter
The BioAssemblyBot® 400 is an intelligent robot used by life scientists to build 3D model systems with increased throughput and precision, alleviating major concerns mentioned above.…
Application Note
Automated dispensing, monitoring, and assay development of hydrogel-based cellular models
Automated dispensing, monitoring, and assay development of hydrogel-based cellular models
3D cellular models that more accurately represent various microenvironments are incredibly important for accurate drug screening and disease modeling.
Scientific Poster
Automation for organoid assays – An integrated system with high-content imaging
Automation for organoid assays – An integrated system with high-content imaging
Three-dimensional (3D) cell models that represent various tissues are being successfully used in drug discovery and disease modeling to study complex biological effects and tissue ar…
Automate your 3D biology high-throughput workflows
Related Products & Services
IN Carta Image Analysis Software
Provides robust, quantitative results from complex biological images and datasets
Featured Applications
3D Cell Models
3D cell cultures offer the advantage of closely recapitulating aspects of human tissues including…
Drug Discovery and Development
For every drug that makes it to the finish line, another nine don’t succeed. This alarming failure…
Lab Automation for High-content Screening
Our automated, high-content screening (HCS) workcell provides an end-to-end solution that helps…
Organoid Innovation Center
Our lab automation solutions include scientists and engineers who can customize our instruments, as…
Organoid Research
Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that are…
Toxicology
Toxicology is the study of adverse effects of natural or man-made chemicals on living organism. It…
Want to save time and resources with an automation-ready solution?
We’re here to help. Our highly qualified team of scientists and engineers can automate systems and entire workflows to meet specific needs of your assay, method, or protocol. Are you ready to explore an automated lab solution—saving time and resources while advancing scientific discovery?