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SpectraMax QuickDrop Micro-Volume Spectrophotometer
One-touch DNA, RNA, and protein quantitation in a full-spectrum micro-volume absorbance spectrophotometer
Standalone instrument with touchscreen and built-in sample ports for small volumes and cuvettes
The SpectraMax® QuickDrop™ Micro-Volume Spectrophotometer quantifies very small amounts of DNA, RNA, oligos, and proteins. The small footprint and touchscreen control allows for easy laboratory setup with minimal investment of time, cost, and effort. The built-in micro-volume sample port allows for working with sample volumes as small as 0.5 µL, while the cuvette port expands sample capacity to include larger volumes.
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Increase sensitivity
The SpectraMax QuickDrop has a four-second read time and no moving parts. It maintains an accurate pathlength, providing you with fast and accurate results regardless of viscosity.
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Easy to use
The large, high-resolution touchscreen offers preconfigured analysis methods, easy setup of customized experiments including kinetic assays, and allows you to work in six different languages.
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Streamline workflows
The spectrophotometer is maintenance-free and requires no calibration. One-swipe cleaning streamlines your workflow and allows you to quickly move from sample to sample.

SpectraMax QuickDrop Micro-Volume Spectrophotometer
Features
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Small footprint
This stand-alone unit with a small footprint does not require a direct connection to a dedicated computer.
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Flexible data analysis
Results can be viewed on the large touchscreen, or data can be exported to a computer for additional analysis using a USB flash drive.
Latest Resources
Applications of SpectraMax QuickDrop Micro-Volume Spectrophotometer
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Absorbance
Learn all about absorbance detection – how it works, how it’s measured, and how it can be used to calculate concentration. We also provide information on common absorbance applications and assays including ELISAs, nucleic acid and protein quantitation, and microbial growth.
DNA/RNA Quantitation
The absorbance of a DNA sample measured at 260 nm on a spectrophotometer or microplate reader can be used to calculate its concentration. Absorbance quantitation works on samples ranging from about 0.25 ug/mL to about 125 ug/mL in a microplate format. Some instrumentation enables the quantitation of very small sample volumes, as little as 2 uL. When greater sensitivity is required, fluorescence methods allow quantitation of as little as a few picograms of DNA.
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Food/Beverage Testing
Beer is one of the world’s most popular beverages. The brewing process mainly involves water, a sugar source, flavoring/bittering agents (hops), and brewer’s yeast. Put simply, the brewer creates a nutrient-rich environment for the yeast to metabolize the sugar into alcohol and CO2 and adds secondary elements that influence flavor. Over time, the brewing process has become much more complex. As such, brewers must have excellent quality control processes to ensure a high-quality and consistent taste for all their batches.
Microbiology and Contaminant
Microbes, including bacteria, have been estimated to make up about 15 percent of the earth’s biomass, and microbes in the human body outnumber human cells by 10 to 1. These microorganisms provide great benefit to us and are also vital to many fields of research from medicine to alternative energy production. On the other hand, monitoring for microbes and the toxic substances they produce is necessary to ensure the safety of pharmaceutical products. Scientists whose research relies on mammalian cells must carefully monitor these cultures for unwanted microbial contaminants to ensure that their experimental results are reliable.
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Protein Detection, Quantitation and Analysis
Protein detection, quantitation, and analysis are central to the investigation of a wide variety of biological processes. Measuring the concentration of protein is necessary to processes ranging from protein purification and labeling to sample preparation for electrophoresis. Protein can be quantitated directly via absorbance at 280 nm, or indirectly using colorimetric (BCA, Bradford, etc.) or fluorometric methods offering advantages such as greater sensitivity. To identify and measure a specific protein within a complex sample, for example, serum or cell lysate, an ELISA may be used.
Resources of SpectraMax QuickDrop Micro-Volume Spectrophotometer
Blog
FDA 21 CFR Part 11 and the importance of regulatory compliance in GMP and GLP labs
FDA 21 CFR Part 11 and the importance of regulatory compliance in GMP and GLP labs
The regulations for food and drug in the United States, described in the Title 21 of the Code of Federal Regulations, and the EudraLex Annex 11 in EU, are critical in ensuring safe…
Blog
Life sciences technology predictions for 2021
Life sciences technology predictions for 2021
For over 30 years, Molecular Devices has been at the forefront of technological advances which have contributed to significant scientific breakthroughs. To kick off the new year, we…
eBook
Streamline beer, wine, and food quality control and safety analyses
Streamline beer, wine, and food quality control and safety analyses
Absorbance microplate readers are widely used in research, drug discovery, bioassay validation, quality control, and manufacturing processes in the pharmaceutical, biotech, food and…
Application Note
DNA and RNA absorbance measurements using SpectraMax Microplate Readers
DNA and RNA absorbance measurements using SpectraMax Microplate Readers
Ultraviolet (UV) measurements in microplates became possible when Molecular Devices introduced the first UV-capable microplate reader. Since then, microplate measurements of DNA, RNA,…
Data Sheet
SpectraMax® QuickDrop™ Micro-Volume Spectrophotometer
SpectraMax® QuickDrop™ Micro-Volume Spectrophotometer
Learn how the QuickDrop Micro-Volume Spectrophotometer can be used to quantify very small amounts of DNA, RNA, oligos, and proteins.
Application Note
Nucleic acid quantitation and analysis using the QuickDrop Spectrophotometer
Nucleic acid quantitation and analysis using the QuickDrop Spectrophotometer
Spectrophotometry is a well-established technique used to quantitate and analyze biological substances. Of these substances, nucleic acids are one of the most routinely measured in…
Application Note
Beer analysis using the QuickDrop UV-Vis Spectrophotometer
Beer analysis using the QuickDrop UV-Vis Spectrophotometer
Beer is one of the world’s most popular beverages, and it can be dated back as early as 6000 BCE from Sumerian artifacts1. The brewing process mainly involves water, a sugar source,…


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SpectraMax QuickDrop Micro-Volume Spectrophotometer

QuickDrop Spectrophotometer Tutorial Videos
Number of Citations*: 56
Latest Citations: For a complete list, please click here .
*Source: https://scholar.google.com/
- Dated: Aug 26, 2020Publication Name: Horticulture, Environment, and Biotechnology
Enhanced detoxification of exogenous toluene gas in transgenic Ardisia pusilla expressing AtNDPK2 gene
The Arabidopsis nucleoside diphosphate kinase 2 (AtNDPK2) gene is known to regulate the cellular redox state, and to enhance tolerance to multiple stressors in plants. In this study, we transferred AtNDPK2 under the stress-inducible promoter SWPA2 into Ardisia pusilla to enhance the plants’ ability to detoxify toluene gas. Thirty transgenic A.… View moreThe Arabidopsis nucleoside diphosphate kinase 2 (AtNDPK2) gene is known to regulate the cellular redox state, and to enhance tolerance to multiple stressors in plants. In this study, we transferred AtNDPK2 under the stress-inducible promoter SWPA2 into Ardisia pusilla to enhance the plants’ ability to detoxify toluene gas. Thirty transgenic A. pusilla lines were confirmed by PCR analysis with AtNDPK2 and NPTII gene-specific primers. In addition, four transgenic A. pusilla lines were further confirmed by Southern blot analysis to verify the gene copy number. Three transgenic lines showed a single-copy transgene insertion, and one transgenic line had two transgene insertions. To test the gene expression of AtNDPK2 in the transgenic A. pusilla lines exposed to and not exposed to toluene treatment, qRT-PCR analysis was performed. The gene expression of AtNDPK2 in transgenic A. pusilla plants exposed to toluene treatment was significantly higher than that of transgenic plants not exposed to toluene treatment. Finally, we measured toluene removal efficiency of the transgenic and non-transgenic A. pusilla lines exposed to toluene-contaminated air. There was a statistically significant difference between the transgenic and non-transgenic A. pusilla lines at all time points (p < 0.001). The highest toluene removal efficiency (797.33 ± 59.41 µg m−3 cm−2 leaf area) was recorded in the transgenic A. pusilla line NDPK2-12-4 after 3 h of exposure to toluene, while the non-transgenic line showed little toluene removal efficiency (206.2 ± 31.19 µg m−3 cm−2 leaf area). These results suggest that the capacity for detoxifying toluene gas is related to the AtNDPK2 gene in A. pusilla. Therefore, this study provides useful results to reduce toluene pollution in indoor air.
Contributors: Chang Ho Ahn, Nan-Sun Kim, Ju Young Shin, Young Ah Lee, Kwang Jin Kim, Jeong Ho Kim, Pil Man Park, Hye Ryun An, Yae-Jin Kim, Won Hee Kim & Su Young Lee
Go to article - Dated: May 06, 2020Publication Name: AMB Express
Survival strategy of Pseudomonas aeruginosa on the nanopillar topography of dragonfly (Pantala flavescens) wing
Discovery of nanopillars on the surface of the insect wings had led to the understanding of its bactericidal property. Nanopillar topography is deterrent to only those bacteria that are attached, or in close contact with the nanopillars. The present study investigated the variation in the viability of Pseudomonas aeruginosa strains PAO1 (virulent… View moreDiscovery of nanopillars on the surface of the insect wings had led to the understanding of its bactericidal property. Nanopillar topography is deterrent to only those bacteria that are attached, or in close contact with the nanopillars. The present study investigated the variation in the viability of Pseudomonas aeruginosa strains PAO1 (virulent) and ATCC 9027 (avirulent) on the wing surface of dragonfly (Pantala flavescens). Viability study indicated that only 0.2% ATCC 9027 survived when incubated with wing for 48 h in Phosphate buffered saline, while under the same conditions 43.47% PAO1 survived. Enumeration of Pseudomonas attached to wing surface suggested that, the number of PAO1 attached on the wing surface was three times lesser than ATCC 9027. Propensity of attachment of P. aeruginosa strains PAO1 and ATCC 9027 on the wing surface investigated using scanning probe microscope indicated that P. aeruginosa ATCC 9027 showed adhesion to 88% of regions and, PAO1 showed adhesion to only 48% regions tested on wing surface. PAO1 survived the bactericidal effect of wing surface by evading attachment. Three clinical isolates tested which showed viability similar to PAO1 strain, also showed lower propensity to attach to wing surface. Transcriptional level analyses using RT-PCR suggested that flagellar genes (fliE and fleS) were downregulated and genes responsible for reversible to irreversible attachment (gcbA and rsmZ) were upregulated in ATCC 9027 than PAO1 on wing surface, indicating relatively higher attachment of ATCC 9027 on wing surface. The study suggests that virulent strains of P. aeruginosa may evade attachment on wing surface. The results gain significance as bioinspired surfaces are being created towards developing antibacterial medical implants and other antibacterial surface applications.
- Dated: Jul 25, 2019Publication Name: International Journal of Applied Pharmaceutics
Expression of the microfold cells in three-dimensional coculture system for in vitro cultivation of human norovirus
Optimization of Caco-2 cells monoculture in the alginate hydrogel beads showed optimum number of cells of 1 × 106 cells/ml, indicated by the intact structure of the beads. Result of SEM showed clear structure of monoculture in the alginate hydrogel beads indicated by the presence of smooth and regular apical surface while the coculture showed… View moreOptimization of Caco-2 cells monoculture in the alginate hydrogel beads showed optimum number of cells of 1 × 106 cells/ml, indicated by the intact structure of the beads. Result of SEM showed clear structure of monoculture in the alginate hydrogel beads indicated by the presence of smooth and regular apical surface while the coculture showed reduced apical surface of M cells. The result of WB showed downregulation of Ulex europaeus antibody expression.
Related Products & Services of SpectraMax QuickDrop Micro-Volume Spectrophotometer
Featured Applications

Absorbance
Learn all about absorbance detection – how it works, how it’s measured, and how it can be used to…

DNA/RNA Quantitation
The absorbance of a DNA sample measured at 260 nm on a spectrophotometer or microplate reader can…

Food/Beverage Testing
Beer is one of the world’s most popular beverages. The brewing process mainly involves water, a…

Microbiology and Contaminant
Microbes, including bacteria, have been estimated to make up about 15 percent of the earth’s…

Protein Detection, Quantitation and Analysis
Protein detection, quantitation, and analysis are central to the investigation of a wide variety of…
How can we help advance your next big discovery?
Our highly-qualified teams are on the frontlines with our customers, conducting remote or on-site product demonstrations, webinars, and more to help you solve your tough research challenges. How can we help you today?
I’d like to…
How can we help advance your next big discovery?
Our highly-qualified teams are on the frontlines with our customers, conducting remote or on-site product demonstrations, webinars, and more to help you solve your tough research challenges. How can we help you today?
I’d like to…