ImageXpress Nano Automated Imaging System
High-content imaging system for your everyday biological needs
Fluorescence imaging platform within reach of every lab
The ImageXpress® Nano Automated Imaging System features a long life, solid state, light engine, and optics to reliably deliver the right assay sensitivity. Capture fine details of a variety of cellular and subcellular assays with this powerful and flexible fluorescent microscopy solution. The system includes MetaXpress® High-Content Image Acquisition and Analysis Software with tools for 2D and 3D imaging and time lapse analysis, as well as a range of needs from ease-of-use through to proprietary assay design.
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Image label-free
Brightfield imaging allows for rapid acquisition without the use of harmful fluorescent agents.
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Streamline image analysis
The modular toolbox in the MetaXpress® software allows for the quick setup of hundreds of routine assays. Choose from our optional selection of turnkey application modules for greater convenience.
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Capture a diverse range of samples
With 2x to 60x magnification, the system offers the flexibility to image whole-well (C. elegans, zebrafish), as well as sub-cellular details (vesicles, organelles).
ImageXpress Nano High-Content Imaging System Virtual Tour
Features
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Large field of view
An entire well of a 384-well plate can be captured in a single image at 4x magnification for faster throughput.
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Automated Stages
Fully automated X, Y, and Z stages with resolution better than 25 nm.
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Wide range of filters and objectives
The system can be configured with different filters or objectives (2-60x) to meet research needs.
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Five fluorescent channels
The system can have up to 5 fluorescent filters installed at one time. The software allows up to 7 channels to be acquired at one time which enables multi-channel fluorescent and transmitted light imaging in one experiment.
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High-speed autofocus
Laser autofocus enables quick, consistent focusing across plates, slides and uneven surfaces.
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Environmental control option
Multi-day, time lapse and live cell assays can be run using the onboard environmental system with options for temprature, humidity, and CO2 control.
MetaXpress high-content image aquisition and analysis software
- Meet high throughput requirements with a scalable, streamlined workflow
- Adapt your analysis tools to tackle your toughest problems, including 3D analysis
- Schedule automatic data transfer between third-party hardware sources and secure database
- Set up hundreds of routinely used HCS assays using MetaXpress software modules
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eBook
Quantitate Neuron Potential
Quantitate Neuron Potential
Gain valuable insights into neurobiology, from evaluation of ion channels to analysis of 3D neuron organoids.
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Flyer
ImageXpress Nano Automated Imaging System
ImageXpress Nano Automated Imaging System
The ImageXpress® Nano Automated Imaging System enables researchers to get better data faster and improve collaborations with peers – anywhere, anytime. Learn more about how this cost effecti…
Applications of ImageXpress Nano Automated Imaging System
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Cardiomyocytes
Stem cells differentiated into cardiomyocytes are used to screen early for potential toxicological effects of drugs, thus helping to avoid investment in development of drugs which will fail in clinical trials due to cardiac toxicity.
Cardiomyocytes
Stem cells differentiated into cardiomyocytes are used to screen early for potential toxicological effects of drugs, thus helping to avoid investment in development of drugs which will fail in clinical trials due to cardiac toxicity.
Live Cell Imaging
Live cell imaging is the study of cellular structure and function in living cells via microscopy. It enables the visualization and quantitation of dynamic cellular processes in real time. Live cell imaging encompasses a broad range of topics and biological applications—whether it is performing long-term kinetic assays or fluorescently labeling live cells.
Live Cell Imaging
Live cell imaging is the study of cellular structure and function in living cells via microscopy. It enables the visualization and quantitation of dynamic cellular processes in real time. Live cell imaging encompasses a broad range of topics and biological applications—whether it is performing long-term kinetic assays or fluorescently labeling live cells.
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Neurite Outgrowth / Neurite Tracing
Neurons create connections via extensions of their cellular body called processes. This biological phenomenon is referred to as neurite outgrowth. Understanding the signaling mechanisms driving neurite outgrowth provides valuable insight into neurotoxic responses, compound screening, and for interpreting factors influencing neural regeneration. Using the ImageXpress Micro system in combination with MetaXpress Image Analysis Software automated neurite outgrowth imaging and analysis is possible for slide or microplate-based cellular assays.
Neurite Outgrowth / Neurite Tracing
Neurons create connections via extensions of their cellular body called processes. This biological phenomenon is referred to as neurite outgrowth. Understanding the signaling mechanisms driving neurite outgrowth provides valuable insight into neurotoxic responses, compound screening, and for interpreting factors influencing neural regeneration. Using the ImageXpress Micro system in combination with MetaXpress Image Analysis Software automated neurite outgrowth imaging and analysis is possible for slide or microplate-based cellular assays.
Stem Cell Research
Pluripotent stem cells can be used for studies in developmental biology or differentiated as a source for organ-specific cells and used for live or fixed cell-based assays on slides or in multi-well plates. The ImageXpress Nano system paired with CellReporterXpress software for analysis has utility in all parts of the stem cells researcher’s workflow from tracking differentiation to quality control to measuring functionality of specific cell types.
Stem Cell Research
Pluripotent stem cells can be used for studies in developmental biology or differentiated as a source for organ-specific cells and used for live or fixed cell-based assays on slides or in multi-well plates. The ImageXpress Nano system paired with CellReporterXpress software for analysis has utility in all parts of the stem cells researcher’s workflow from tracking differentiation to quality control to measuring functionality of specific cell types.
Resources of ImageXpress Nano Automated Imaging System
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eBook
Quantitate Neuron Potential
Quantitate Neuron Potential
Gain valuable insights into neurobiology, from evaluation of ion channels to analysis of 3D neuron organoids.
-
Flyer
ImageXpress Nano Automated Imaging System
ImageXpress Nano Automated Imaging System
The ImageXpress® Nano Automated Imaging System enables researchers to get better data faster and improve collaborations with peers – anywhere, anytime. Learn more about how this cost ef…
Application Note
High-throughput screening of single-cell contractile force using FLECS Technology
High-throughput screening of single-cell contractile force using FLECS Technology
The ability of mammalian cells to generate mechanical forces—to push, pull, or squeeze—is an intrinsic capability that is used by cells both individually and together as tissue to…
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Application Note
Phenotypic characterization of anti-cancer drug effects using automated imaging
Phenotypic characterization of anti-cancer drug effects using automated imaging
Discovery and evaluation of anti-cancer therapies is an active area of research that includes development of cell-based models, screening for novel drugs, comparison of drug efficacy,…
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Application Note
Quantitate GPCR activation using automated cell imaging and analysis
Quantitate GPCR activation using automated cell imaging and analysis
GPCRs are the largest group of signal transducing transmembrane proteins, constituting roughly 4% of the proteincoding genome. They play integral roles in a wide range of biological…
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Application Note
Transmitted light image analysis for cell count and assessment of cytotoxicity effects
Transmitted light image analysis for cell count and assessment of cytotoxicity effects
Numerous biological applications require monitoring of cell number, cell health, confluency, and proliferation during multiple time points without fluorescent markers or other labels.…
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Application Note
Streamline assessment of DNA damage using the ImageXpress Nano system
Streamline assessment of DNA damage using the ImageXpress Nano system
Assessing damage to DNA or chromosomes is frequently addressed with research applications because of its implications in diverse diseases including genetic mutations, cancer, and aging…
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Application Note
Assessment of neurotoxicity and neuronal development using induced pluripotent stem cell-based neurite outgrowth assay
Assessment of neurotoxicity and neuronal development using induced pluripotent stem cell-based neurite outgrowth assay
Growing concerns about the increased prevalence of untested chemicals in the environment has created a pressing need to develop reliable and efficient screening tools to identify…
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Application Note
Phenotypic characterization of toxic compound effects on cardiomyocytes derived from induced pluripotent stem cells
Phenotypic characterization of toxic compound effects on cardiomyocytes derived from induced pluripotent stem cells
Cardiotoxicity remains a primary cause for drug attrition during clinical trials and post-marketing. While it is believed that a significant percentage of cardiovascular diseases are…
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eBook
Cellular Imaging Insights
Cellular Imaging Insights
Gain insights and expedite studies for 2D and 3D cellular structures using automated cellular imaging.
Brochure
Imaging Solutions to Answer Your Biological Questions
Imaging Solutions to Answer Your Biological Questions
Learn about our imaging family and which solution is best suited to answer your biological questions.
Scientific Poster
In Vitro Cardiotoxicity and Neurotoxicity Assessment of Environmental Chemicals Using Organotypic Human Induced Pluripotent Stem Cell-Derived Models
In Vitro Cardiotoxicity and Neurotoxicity Assessment of Environmental Chemicals Using Organotypic Human Induced Pluripotent Stem Cell-Derived Models
An increased prevalence of neurological and cardiovascular disorders, possibly attributed to environmental toxicant exposures, has generated an interest in developing reliable and effic…
Videos & Webinars
Accelerate your screening with high-content and automated imaging
Accelerating study of viral infection and therapeutics with microplate-based detection and high-throughput screening
ImageXpress Nano High-Content Imaging System Virtual Tour
Magnetic 3D Bioprinting, 3D Cell Culture in a 2D Workflow
LabTube Meets Molecular Devices & MIMETAS, Susan Murphy & Sebastiaan Trietsch
Plate annotation and curve fitting in MetaXpress
Quickstart Guide: Plate acquisition on the ImageXpress Micro Confocal using MetaXpress
Quickstart Guide: Review images on the ImageXpress Micro Confocal using MetaXpress
Basic workflow from image acquisition to analysis on the ImageXpress Micro Confocal using MetaXpress
Developing high-throughput organ-on-a-chip tissue models for drug discovery using high-content imaging
Related Products & Services of ImageXpress Nano Automated Imaging System
Featured Applications
Cardiomyocytes
Stem cells differentiated into cardiomyocytes are used to screen early for potential toxicological…
Live Cell Imaging
Live cell imaging is the study of cellular structure and function in living cells via microscopy.…
Neurite Outgrowth / Neurite Tracing
Neurons create connections via extensions of their cellular body called processes. This biological…
Stem Cell Research
Pluripotent stem cells can be used for studies in developmental biology or differentiated as a…