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Fluorescence imaging platform within reach of every lab

The ImageXpress® Nano Automated Imaging System features a long life, solid state, light engine, and optics to reliably deliver the right assay sensitivity. Capture fine details of a variety of cellular and subcellular assays with this powerful and flexible fluorescent microscopy solution. The system includes MetaXpress® High-Content Image Acquisition and Analysis Software with tools for 2D and 3D imaging and time lapse analysis, as well as a range of needs from ease-of-use through to proprietary assay design.

  • Image label-free

    Image label-free

    Brightfield imaging allows for rapid acquisition without the use of harmful fluorescent agents.

  • Streamline image analysis

    Streamline image analysis

    The modular toolbox in the MetaXpress® software allows for the quick setup of hundreds of routine assays. Choose from our optional selection of turnkey application modules for greater convenience.

  • Capture a diverse range of samples

    Capture a diverse range of samples

    With 2x to 60x magnification, the system offers the flexibility to image whole-well (C. elegans, zebrafish), as well as sub-cellular details (vesicles, organelles).

ImageXpress Nano High Content

ImageXpress Nano High-Content Imaging System Virtual Tour

Features

  • Large field of view

    An entire well of a 384-well plate can be captured in a single image at 4x magnification for faster throughput.

  • Automated Stages

    Fully automated X, Y, and Z stages with resolution better than 25 nm.

  • Wide range of filters and objectives

    The system can be configured with different filters or objectives (2-60x) to meet research needs.

  • Five fluorescent channels

    The system can have up to 5 fluorescent filters installed at one time. The software allows up to 7 channels to be acquired at one time which enables multi-channel fluorescent and transmitted light imaging in one experiment.

  • High-speed autofocus

    Laser autofocus enables quick, consistent focusing across plates, slides and uneven surfaces.

  • Environmental control option

    Environmental control option

    Multi-day, time lapse and live cell assays can be run using the onboard environmental system with options for temprature, humidity, and CO2 control.

Introducing the MetaXpress 3D Analysis Toolkit

MetaXpress high-content image aquisition and analysis software

 

  • Meet high throughput requirements with a scalable, streamlined workflow
  • Adapt your analysis tools to tackle your toughest problems, including 3D analysis
  • Schedule automatic data transfer between third-party hardware sources and secure database
  • Set up hundreds of routinely used HCS assays using MetaXpress software modules

Applications of ImageXpress Nano Automated Imaging System

  • Cardiomyocytes

    Cardiomyocytes

    Stem cells differentiated into cardiomyocytes are used to screen early for potential toxicological effects of drugs, thus helping to avoid investment in development of drugs which will fail in clinical trials due to cardiac toxicity.

    Read Application Note 

    Live Cell Imaging

    Live Cell Imaging

    Live cell imaging is the study of cellular structure and function in living cells via microscopy. It enables the visualization and quantitation of dynamic cellular processes in real time. Live cell imaging encompasses a broad range of topics and biological applications—whether it is performing long-term kinetic assays or fluorescently labeling live cells.

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  • Neurite Outgrowth / Neurite Tracing

    Neurite Outgrowth

    Neurons create connections via extensions of their cellular body called processes. This biological phenomenon is referred to as neurite outgrowth. Understanding the signaling mechanisms driving neurite outgrowth provides valuable insight into neurotoxic responses, compound screening, and for interpreting factors influencing neural regeneration. Using the ImageXpress Micro system in combination with MetaXpress Image Analysis Software automated neurite outgrowth imaging and analysis is possible for slide or microplate-based cellular assays.

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    Stem Cell Research

    Stem Cell Research

    Pluripotent stem cells can be used for studies in developmental biology or differentiated as a source for organ-specific cells and used for live or fixed cell-based assays on slides or in multi-well plates. The ImageXpress Nano system paired with CellReporterXpress software for analysis has utility in all parts of the stem cells researcher’s workflow from tracking differentiation to quality control to measuring functionality of specific cell types.

    Read Application Note 

Specifications & Options of ImageXpress Nano Automated Imaging System

Resources of ImageXpress Nano Automated Imaging System

Videos & Webinars

Accelerate your Screening with Automated Imaging

Accelerate your screening with high-content and automated imaging

Microplate based Detection

Accelerating study of viral infection and therapeutics with microplate-based detection and high-throughput screening

ImageXpress Nano High Content

ImageXpress Nano High-Content Imaging System Virtual Tour

Magnetic 3D

Magnetic 3D Bioprinting, 3D Cell Culture in a 2D Workflow

Labtube Meets SLAS

LabTube Meets Molecular Devices & MIMETAS, Susan Murphy & Sebastiaan Trietsch

Plate annotation and curve fitting in MetaXpress

Plate annotation and curve fitting in MetaXpress

Plate acquisition on ImageXpress Micro Confocal using MetaXpress

Quickstart Guide: Plate acquisition on the ImageXpress Micro Confocal using MetaXpress

Review images on ImageXpress Micro Confocal using MetaXpress

Quickstart Guide: Review images on the ImageXpress Micro Confocal using MetaXpress

Image analysis on ImageXpress Micro Confocal using MetaXpress

Basic workflow from image acquisition to analysis on the ImageXpress Micro Confocal using MetaXpress

Developing High Throughput Organ on a Chip Tissue

Developing high-throughput organ-on-a-chip tissue models for drug discovery using high-content imaging

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Featured Applications