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What you will find in this guide

This guide serves as an information and data resource for electrophysiologists. It covers a broad scope of topic ranging from the biological basis of bioelectricity and a description of the basic experimental setup to a discussion of mechanisms of noise and data analysis.

The Axon Guide third edition is a tool benefiting both the novice and the expert electrophysiologist. Newcomers to electrophysiology will gain an appreciation of the intricacies of electrophysiological measurements and the requirements for setting up a complete recording and analysis system. For experienced electrophysiologists, we include in-depth discussions of selected topics, such as advanced methods in electrophysiology and noise.

Table of contents

  • 1. Bioelectricity
  • 2 The Laboratory Setup
  • 3. Instrumentation for Measuring Bioelectric Signals from Cells
  • 4. Microelectrodes and Micropipettes
  • 5. Advanced Methods in Electrophysiology
  • 6. Signal Conditioning and Signal Conditioners
  • 7. Transducers
  • 8. Laboratory Computer Issues and Considerations
  • 9. Acquisition Hardware
  • 10. Data Analysis
  • 11. Noise in Electrophysiological Measurements
  • Appendix A: Guide to Interpreting Specifications
Axon Guide Content
Axon Guide Content
Axon Guide Content
Axon Guide Content
Axon Guide Content


The most comprehensive laboratory techniques workbook—with over 300 pages—to support electrophysical and biophysical research

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