September 2018
cellular imaging • high-throughput screening • colony selection
microplate detection • analysis
Application Spotlight
NEW Assay apoptosis in magnetically bioprinted
HepG2 spheroids

A variety of methods for transforming 2D cultures into 3D spheroids have been devised but require a long time to form spheroids that can be difficult to handle. See how HepG2 cells can be bioprinted using the magnetic 3D cell culture system from Greiner Bio-One (m3D). The resulting spheroids are imaged on the SpectraMax® i3x reader with MiniMax™ cytometer.
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Webinar Spotlight
NEW Achieving higher throughput with multiplexed
phage display

Multiplexed phage display provides a simple, robust, and seamless high-throughput-ready version of phage display that can simultaneously screen and bioinformatically analyze up to 96 peptide phage libraries in parallel. To accommodate the large number of potential lead peptides from the screening, the ForteBio Octet® System was used to characterize streptavidin peptide fusions generated by in vitro translation.
Webinar details: September 27, 2018 at 8:00 AM PDT

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Application Spotlight
NEW Faster ELISA results with CatchPoint SimpleStep
ELISA kits

Typical ELISA protocols are time-consuming, with multiple incubation and wash steps. CatchPoint® SimpleStep ELISA® technology drastically reduces assay time by forming and capturing the antibody-analyte sandwich complex in the well of a microplate precoated with an immunoaffinity tag in a single step.
-Reduce time to results with a single-wash, 90-minute protocol
-Generate standard curves and quantitate results quickly
-Increase assay signal and dynamic range with fluorescent readout
Application Spotlight
NEW Optimization of NaV1.5 channel assay
Voltage-gated ion channels are present in the excitable cell membranes of heart, skeletal muscle, brain and nerve cells. Blocking or modulating such channels can have a therapeutic effect or may interfere with normal cell function. Here, CHL cells transfected with the cardiac NaV1.5 channel are used to demonstrate differences in membrane potential assay functionality with tetrodotoxin and lidocaine & show optimization results with the FLIPR® Membrane Potential Assay Kits.

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Application Spotlight
NEW Detection of Autophagy using ImageXpress™ Pico system
Autophagy and its dysregulation has been found to play an important role in neurodegenerative diseases and cancers, therefore the discovery of novel therapeutic targets along this process has emerged as a promising approach for drug therapies. In our application note, learn a method for detecting autophagy particles which can be used for assay development and quantitation of the compound effects on the process of autophagy.
Contest Spotlight
NEW Imaging Contest
Get recognized for your scientific research using your ImageXpress imaging system. Submit an image (or two) to the Molecular Devices Imaging Contest. Winners will be featured in the 2019 Molecular Devices calendar. Click on the link to submit an entry or vote for your favorites.

Submit Entry
Upcoming Events
ForteBio User Group Meeting
September 11, 2018
Boston, MA USA

September 11-14, 2018
Basel, Switzerland
Booth #A48

September 12-13, 2018
Copenhagen, Denmark
Booth #19

September 14-16, 2018
London, UK
Booth #21

September 19-20, 2018
Boston, MA USA
Molecular Devices High-Content Imaging User Meeting
September 19, 2018
Boston, MA USA

Discovery on Target
September 25–28, 2018
Boston, MA USA

October 2-5, 2018
Utrecht, Netherlands

October 3-4, 2018
Lausanne, Switzerland

BioProduction Congress
October 8-10, 2018
Dublin, Ireland
Booth #59
(Join ForteBio, our new Biologics business unit)

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