Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus Anthracis Spores

RN Kirchdoerfer, et al., 20(3), 479-486, Structure, 2012

In this study, interactions of variable lymphocyte receptor 4 (VLR4) from jawless fish and the Bacillus anthracis spore protein BcIA are characterized using the Octet RED platform. Various biotinylated BcIA C-terminal domain variants were immobilized on Streptavidin biosensors and incubated with a dilution series of truncated monomeric VLR4.

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