The Carboxy-terminus of BAK1 Regulates Kinase Activity and is Required for Normal Growth of Arabidopsis

Oh MH, et al., 5:16, Front Plant Sci, 2014

The authors performed structural and functional analysis on the interaction of the brassinosteroid-insensitive 1 (BRI1) receptor kinase and its co-receptor BRI1-associated receptor kinase (BAK1) in order to better understand the plant receptor kinase signaling process as well as the control mechanisms of Arabidopsis growth. Binding studies were performed using the Octet QK system with Streptavidin biosensors to further elucidate the binding kinetics and characteristics of these two targets and the key role the carboxy terminal domain plays in the binding and phosphorylation events.

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