Sulfolobus replication factor C stimulates the activity of DNA polymerase B1

Xing X, et al., doi: 10.1128/JB.01552-14, J Bacteriol, 2014

The authors performed functional analysis on the replication factor C (RFC) of Sulfolobus solfataricus , a thermoacidophilic crenarchaeon to further elucidate the mechanism and role the RFC plays in the activation of DNA polymerase B and DNA replication. Binding studies were carried out on the Octet RED system and Streptavidin biosensors were used.

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