Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D

Bhattacharya S, et al., 111(25):9103-8, Proc Natl Acad Sci U S A, 2014

In this report, the authors performed detailed crystallography and biochemical functional analysis on TATA binding protein-associated factors 1 and 7 (TAF1 and TAF7) to better define how these two key subunit proteins of the transcription factor II D complex bind chromatin to control gene expression. Peptide binding studies were carried out on the Octet RED384 system. Streptavidin biosensors were used.

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