Strategies Using Bio-Layer Interferometry Biosensor Technology for Vaccine Research and Development

Petersen RL, 7(4). pii: E49, Biosensors (Basel), 2017

Over the years, Bio-Layer Interferometry (BLI) biosensor technology has contributed immensely to vaccine research and development in numerous ways. Reviewed herein are some key BLI based strategies that are commonly used in human vaccine research and development such as epitope-design/epitope-capture approaches, antibody-design /antibody-capture strategies, virus capture strategies, and nucleic acid capture approaches. Dip and Read BLI assay format can handle crude samples and offers high-throughput high-precision real-time biomolecular interaction analysis, making it a very powerful platform in the field of vaccine research and development.

Read More