Reducing Protein Adsorption with Polymer-grafted Hyaluronic Acid Coatings

Ramadan MH, et al., 30(25):7485-95, Langmuir, 2014

The authors described the modification of hyaluronic acid (HA) used for coating a broad range of biomaterial surfaces as a means to reducing protein adsorption and thereby generate more accurate test results. The preparation and characterization of HA was first monitored by chromatography and atomic force microscopy and confirmed by BLI analysis. Real-time binding experiments were performed on the Octet RED system. Aminopropylsilane (APS) biosensors were used.

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