Receptor mimicry by antibody F045-092 Facilitates Universal Binding to the H3 Subtype of Influenza Virus

Lee PS, et al., 2.718055556, Nat Commun, 2014

The authors performed structural and functional characterization of F045-092, a monoclonal antibody isolated from a human B lymphocyte derived phage-display library which showed strong broadly neutralizing activity against H3 influenza virus and providing greater insight into the development of a pan-H3 vaccine. Binding kinetics were determined on the Octet RED system. Streptavidin biosensors were used.

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