N332-Directed Broadly Neutralizing Antibodies Use Diverse Modes of HIV-1 Recognition: Inferences from Heavy-Light Chain Complementation of Function

Pancera, M, et al., 8(2):e55701, PLoS One, 2013

In this study of broadly neutralizing antibodies that target the N332 site of HIV-1 gp120, complementation between 12 heavy chains and 12 light chains was characterized. Expression levels for a panel of transiently transfected antibodies were quantified using the Octet RED96 system with Anti-human IgG Fc biosensors.

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