Modulation of mAb Quality Attributes Using Microliter Scale Fed-batch Cultures

Rouiller Y, et al., doi: 10.1002/btpr.1921, Biotechnol Prog, 2014

The authors optimized a high-throughput process development method to test the effects of different experimental inputs (cell lines and media formulation) on both process performance and product quality of monoclonal antibody production to determine if earlier identification of cell lines and product can be made. Titer quantification of mAbs was performed on the Octet QKe using Protein A biosensors.

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