Increasing Stability of Antibody via Antibody Engineering: Stability Engineering on an Anti-hVEGF

Wang S, et al., doi: 10.1002/prot.24626, Proteins, 2014

The authors designed and integrated computer-aided engineering protocols to optimize and improve antibody structure, expression, activity, specificity, thermo-stability and storage throughout the antibody development process. Affinities of the different antibody variants were tested on the Octet QKe system and Streptavidin biosensors were used.

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