Helicobacter Pylori FlhA Binds the Sensor Kinase and Flagellar Gene Regulatory Protein FlgS with High Affinity

Tsang J, et al., 197(11):1886-92, J Bacteriol, 2015

This study provides additional insights into flagellar assembly in Helicobacter pylori. The high affinity interaction between Flagellar Gene Regulatory Protein (Flgs) and FlhA suggest an additional role for FlhA in flagellar assembly. A Pall ForteBio Octet QK system equipped with Streptavidin Biosensor probes was used to capture biotinylated peptides representing residues 1 to 25 of FlhA. The analytes used in this investigation had FlgS or a shorter version called FlgSc.

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