Evaluation of the Potency of the Anti-idiotypic Antibody Ab2/3H6 Mimicking gp41 as an HIV-1 Vaccine in a Rabbit Prime/Boost Study

Mader, A., Kunert, R., 7(6), e39063, PLoS One , 2012

The authors characterize an anti-ideotypic antibody of interest in HIV-1 vaccine strategies. Affinity analysis and competition assays were performed using the Octet QK system with Streptavidin biosensors. Biotinylated gp140 or a biotinylated epitope of the 2F5 mAb were immobilized on SA biosensors for these studies.

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