Challenges in Developing Bioanalytical Assays for Characterization of Antibody-Drug Conjugates

Stephan, J.P. ; Kozak, K R.; Wong, W.L., 3(6), 677-700, Bioanalysis, 2011

In this article scientists at Genentech review the different bioanalytical strategies that have been implemented to characterize various antibody-drug conjugates (ADCs) and discuss the challenges and issues associated with these approaches. The Octet platform is discussed as a convenient alternative to fluidics-based systems for the analysis of ADCs.

Read More