Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Non-Human Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

Saunders K, et al., doi: 10.1128/JVI.00908-15, J Virol, 2015

This is a proof-of-concept study to show anti-HIV antibody gene transfer as a viable option to protect primates against infection by HIV. A Pall ForteBio Octet RED384 system was used to investigate IgG binding to plasma samples. Amine coupling was used to capture antibodies to AR2G biosensors. The macaques plasma samples were diluted into a 1% BSA-PBS to minimize nonspecific interactions.

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