Biophysical Methods for Identifying Fragment-Based Inhibitors of Protein-Protein Interactions

Pfaff S, et al., 1278:587-613, Methods Mol Biol, 2015

This book chapter describes most common fragment screening methods that are widely used in the Fragment-Based Lead Discovery (FBLD). It highlights the use of Pall ForteBio Octet RED like platforms as alternatives to Biacore 4000 SPR with additional capabilities such as the throughput, automation, sensitivity, and innovativeness in execution.

Read More