Amplification Systems of Weak Interaction Biosensors: Applications and Prospects

Wang X, et al., DOI:, Emerald Insight, 2015

This is a review article on the prospects of biosensor methods that are being used for the investigation of weak interactions. It describes BLI platform (Pall ForteBio) as a viable alternative to Biacore SPR with distinct advantages such as the multichannel detection, high quality reagent availability, absence of the microfluidics, low cost, etc. The authors also appreciate the fact that there is an increased market share for BLI biosensors. This article highlights a signal amplification strategy known as the G protein signaling cascade amplification system for weaker interactions.

Read More