Citations : Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection

The development of a safe and effective vaccine is a key requirement to overcoming the COVID-19 pandemic. Recombinant proteins represent the most reliable and safe vaccine approach but generally require a suitable adjuvant for robust and durable immunity. We used the SARS-CoV-2 genomic sequence and in silico structural modelling to design a recombinant spike protein vaccine (Covax-19^™).

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Contributors: LeiLia, Yoshikazu Honda-Okubo, Ying Huang, HyesunJang, Michael A. Carlock, Jeremy Baldwin, Sakshi Piplani, Anne G.Bebin-Blackwell, DavidForgacs, Kaori Sakamoto, Alberto Stella, Stuart Turville, Tim Chataway, Alex Colella, Jamie Triccas, Ted M. Ross, Nikolai Petrovsky