ImageXpress Micro Confocal

Number of Citations*: 898

Latest Citations: For a complete list, please click here.

High-throughput imaging: Focusing in on drug discovery in 3D

L Li, Q Zhou, TC Voss, KL Quick, DV LaBarbera - Methods, 2016 - Elsevier

… IN Cell Analyzer 6000, GE Healthcare, Confocal (laser based). ImageXpress Ultra, Molecular Devices, Confocal (laser based). ImageXpress Micro Confocal, Molecular Devices, Confocal (LED based). Arrayscan XTI, ThermoFisher, Confocal (LED based) …

Cited by 38 Related articles All 7 versions


Fragment screening at adenosine-A3 receptors in living cells using a fluorescence-based binding assay

LA Stoddart, AJ Vernall, JL Denman, SJ Briddon… - Chemistry & biology, 2012 - Elsevier

… Subsequently, a confocal imaging plate reader (ImageXpress Ultra) was used for automated capture of four images per well … CA200645 and YFP images were then obtained on the ImageXpress Ultra confocal plate reader after a further 30 min …

Cited by 54 Related articles All 11 versions


Phenotypic characterization of toxic compound effects on liver spheroids derived from iPSC using confocal imaging and three-dimensional image analysis

O Sirenko, MK Hancock, J Hesley, D Hong… - Assay and drug …, 2016 -

… Disclosure Statement. OS, JH, DH, AC, and JG are employed by Molecular Devices LLC, which sells the ImageXpress Micro Confocal system and MetaXpress software; MKH, CBC, and DAM are employed by Cellular Dynamics Int., which provides iPSC-derived cells …

Cited by 20 Related articles All 8 versions


Effect of a toggle switch mutation in TM6 of the human adenosine A3 receptor on Gi protein‐dependent signalling and Gi‐independent receptor internalization

LA Stoddart, B Kellam, SJ Briddon… - British journal of …, 2014 - Wiley Online Library

… Images were obtained using an ImageXpress Ultra confocal plate reader (Molecular Devices, Sunnyvale, CA, USA). Four central images were obtained per well using a Plan Fluor 40x NA0.6 extra-long working distance objective …

Cited by 14 Related articles All 15 versions


Small molecule mediated proliferation of primary retinal pigment epithelial cells

JG Swoboda, J Elliott, V Deshmukh… - ACS chemical …, 2013 - ACS Publications

… DMSO (0.2% v/v) for an EdU proliferation assay. EdU-positive cells were quantified using high-content imaging (ImageXpress Ultra Confocal High Content Screening System). In non-proliferating RPE cells at passage 6, 25 …

Cited by 7 Related articles All 4 versions


Towards a therapy for Angelman syndrome by targeting a long non-coding RNA

L Meng, AJ Ward, S Chun, CF Bennett, AL Beaudet… - Nature, 2015 -

… 26 . For the high-throughput in vitro ASO screen, the plates were imaged with ImageXpress Ultra confocal system (Molecular Device) and then further processed with the MetaXpress software (Molecular Device). Typically 200 …

Cited by 161 Related articles All 12 versions


Live cell imaging: An industrial perspective

T McCann - Live Cell Imaging, 2010 - Springer

… Molecular Devices. ImageXpress Ultra. Yes – true confocal. PMTs. 2 to 4× laser. 4. ? No … Molecular Devices'' ImageXpress ULTRA confocal HCS/A imager uses a conventional point-scanning confocal beam and is also marketed as a high-throughput system for primary screening …

Cited by 3 Related articles All 5 versions

Screening for Cancer Therapeutics Using Spheroids: Implementing High-Throughput Confocal Imaging Using 3D Models

J Hesley, O Sirenko - Genetic Engineering & Biotechnology News, 2016 -

… Imaging Spheroids. Spheroids were visualized using the ImageXpress ® Micro Confocal High-Content Imaging System at either 10x or 20x magnification. Confocal optics provide the ability to image a thinner optical section of the spheroid than widefield optics …

Cited by 1 Related articles

Downregulation of TIGAR sensitizes the antitumor effect of physapubenolide through increasing intracellular ROS levels to trigger apoptosis and autophagosome …

T Ma, Y Zhang, C Zhang, JG Luo, LY Kong - Biochemical pharmacology, 2017 - Elsevier … 96-well glass culture plate (Corning, USA). After incubated for 12 h, cells were treated with PB after transfection and images were taken by ImageXpress® Micro Confocal (Molecular Devices, USA). 2.11. Immunofluorescence …

Cited by 4 Related articles All 4 versions

quantitative assessment of agonist-stimulated intracellular accumulation of the adenosine-a1 receptor by high content screening

H Chilvers, S Hill, S Briddon - British Journal of …, 2012 -

… incubation with agonist (90min,37°C). Cells were then washed before fixation in 3% (v/v) paraformaldehyde, nuclei stained with Hoechst 33342 (2mg/ml) and images (4 sites/well in triplicate) obtained using an ImageXpress Ultra confocal plate reader (Molecular Devices) …

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Number of Citations*: 898

Latest Citations: For a complete list, please click here.