FLIPR High-Throughput Cellular Screening System

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FLIPR: a new instrument for accurate, high throughput optical screening

KS Schroeder, BD Neagle - Journal of Biomolecular …, 1996 -

Modern optical screening assays demand high data throughput along with uncompromised data fidelity. FLIPR (Fluorescent Imaging Plate Reader) was developed to perform quantitative optical screening for cell-based kinetic assays. FLIPR incorporates an …

Cited by 213 Related articles All 2 versions [PDF] 

c-FLIPR, a new regulator of death receptor-induced apoptosis

A Golks, D Brenner, C Fritsch, PH Krammer… - Journal of Biological …, 2005 - ASBMB

Abstract c-FLIPs (c-FLICE inhibitory proteins) play an essential role in regulation of death receptor-induced apoptosis. Multiple splice variants of c-FLIP have been described on the mRNA level; so far only two of them, c-FLIP L and c-FLIP S, had been found to be expressed …

Cited by 309 Related articles All 10 versions [PDF]

Measurement of [Ca2+] Using the Fluorometric Imaging Plate Reader (FLIPR)

E Sullivan, EM Tucker, IL Dale - Calcium Signaling Protocols, 1999 - Springer

Ionized calcium plays a major role in the regulation of cellular processes in both eukaryotic and prokaryotic cells (1). A wide variety of cell surface receptors and ion channels utilize a calcium signal to initiate events such as cell motility, contraction, and secretion. To a large …

Cited by 167 Related articles All 6 versions

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