Citations

FLIPR Tetra High-Throughput Cellular Screening System

Number of Citations*: 13100

Latest Citations: For a complete list, please click here.

Characterization of the mouse cold‐menthol receptor TRPM8 and vanilloid receptor type‐1 VR1 using a fluorometric imaging plate reader (FLIPR) assay

HJ Behrendt, T Germann, C Gillen… - British journal of …, 2004 - Wiley Online Library

Abstract TRPM8 (CMR1) is a Ca 2+-permeable channel, which can be activated by low temperatures, menthol, eucalyptol and icilin. It belongs to the transient receptor potential (TRP) family, and therefore is related to vanilloid receptor type-1 (VR1, TRPV1). We tested …

Cited by 399 Related articles All 13 versions

[HTML] wiley.com

FLIPR: a new instrument for accurate, high throughput optical screening

KS Schroeder, BD Neagle - Journal of Biomolecular …, 1996 - journals.sagepub.com

Modern optical screening assays demand high data throughput along with uncompromised data fidelity. FLIPR (Fluorescent Imaging Plate Reader) was developed to perform quantitative optical screening for cell-based kinetic assays. FLIPR incorporates an …

Cited by 208 Related articles All 2 versions

[PDF] sagepub.com

Measurement of [Ca2+] Using the Fluorometric Imaging Plate Reader (FLIPR)

E Sullivan, EM Tucker, IL Dale - Calcium Signaling Protocols, 1999 - Springer

Ionized calcium plays a major role in the regulation of cellular processes in both eukaryotic and prokaryotic cells (1). A wide variety of cell surface receptors and ion channels utilize a calcium signal to initiate events such as cell motility, contraction, and secretion. To a large …

Cited by 166 Related articles All 6 versions

c-FLIPR, a new regulator of death receptor-induced apoptosis

A Golks, D Brenner, C Fritsch, PH Krammer… - Journal of Biological …, 2005 - ASBMB

Abstract c-FLIPs (c-FLICE inhibitory proteins) play an essential role in regulation of death receptor-induced apoptosis. Multiple splice variants of c-FLIP have been described on the mRNA level; so far only two of them, c-FLIP L and c-FLIP S, had been found to be expressed …

Cited by 302 Related articles All 10 versions

[PDF] jbc.org

Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell‐line using FLIPR

D Smart, JC Jerman, SJ Brough… - British journal of …, 1999 - Wiley Online Library

The cellular mechanisms underlying the physiological effects of the orexins are poorly understood. Therefore, the pharmacology of the recombinant human orexin receptors was studied using FLIPR. Intracellular calcium ([Ca2+] i) was monitored in Chinese hamster …

Cited by 176 Related articles All 9 versions

[HTML] wiley.com

Characterization using FLIPR of rat vanilloid receptor (rVR1) pharmacology

JC Jerman, SJ Brough, R Prinjha… - British journal of …, 2000 - Wiley Online Library

Please review our Terms and Conditions of Use and check box below to share full-text version of article … I have read and accept the Wiley Online Library Terms and Conditions of Use … Use the link below to share a full-text version of this article with your friends and colleagues …

Cited by 128 Related articles All 9 versions

[HTML] wiley.com

Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology

D Smart, JC Jerman, MJ Gunthorpe, SJ Brough… - European journal of …, 2001 - Elsevier

A full pharmacological characterisation of the recently cloned human vanilloid VR1 receptor was undertaken. In whole-cell patch clamp studies, capsaicin (10 μM) elicited a slowly activating/deactivating inward current in human embryonic kidney (HEK293) cells stably …

Cited by 106 Related articles All 5 versions

Validation of FLIPR membrane potential dye for high throughput screening of potassium channel modulators

KL Whiteaker, SM Gopalakrishnan… - Journal of …, 2001 - journals.sagepub.com

A fluorescence-based assay using the FLIPR Membrane Potential Assay Kit (FMP) was evaluated for functional characterization and high throughput screening (HTS) of potassium channel (ATP-sensitive Ki channel; KATP) modulators. The FMP dye permits a more …

Cited by 92 Related articles All 4 versions

[PDF] sagepub.com

Evaluation of SDF‐1/CXCR4‐induced Ca2+ signaling by fluorometric imaging plate reader (FLIPR) and flow cytometry

K Princen, S Hatse, K Vermeire… - Cytometry Part A …, 2003 - Wiley Online Library

Background The chemokine receptors CXCR4 and CCR5 are the main coreceptors for human immunodeficiency virus (HIV) 1 to enter its target cells. The antiviral activity of their natural ligands (stromal cell‐derived factor 1 [SDF‐1], regulated on activation normal T‐cell …

Cited by 93 Related articles All 7 versions

[PDF] wiley.com

A homolog of formyl peptide receptor-like 1 inhibitor from Staphylococcus aureus (FLIPr-Like) that inhibits FPRL1 and FPR

C Prat, PJ Haas, J Bestebroer… - The Journal of …, 2009 - Am Assoc Immnol

The members of the formylated peptide receptor (FPR) family are involved in the sensing of chemoattractant substances, including bacteria-derived N-formylated peptides and host- derived peptides and proteins. We have recently described two chemoattractant receptor …

Cited by 62 Related articles All 8 versions

[PDF] jimmunol.org

 

Number of Citations*: 13100

Latest Citations: For a complete list, please click here.

*Source: https://scholar.google.com/