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Efficient cell washing with minimal cell loss and optimal assay performance
The AquaMax® Microplate Washer is a fully self-contained system, configurable for both 96- and 384-well microplates. Use preconfigured wash, soak, and aspiration protocols or create your own multi-step protocol using the simple touchscreen interface. For biochemical assays, the washer removes unbound material and unreacted reagents. For cell-based assays, the washer has the option for 96- or 384-well cell wash heads with angled pins to allow extremely gentle washing of weakly adherent cell types.
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Install easily
The washer does not require external pumps or a computer to operate, minimizing bench space. Interchangeable wash heads can be installed in seconds without tools, calibration, or alignment.
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Eliminate plate indexing
Aspiration and dispensing of 96- and 384-wells occur simultaneously in all wells leading to high-precision assays and faster microplate processing without mechanical plate indexing or quadrant processing.
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Run multiple wash protocols
Two- or four-fluid inlets with matching color-coded tubing facilitate quick assembly of the buffer and solution bottles and allow multiple wash protocols to be run without switching bottles.

AquaMax Microplate Washer
Features
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Trouble-free operation
Comprehensive cleaning protocols can be activated at the touch of a button for trouble-free operation. A standby feature keeps the washer primed and probe tips submersed in buffer for instant startup.
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Versatility
Precise dispense and aspiration control allow processing without cell disruption. Fast sequential, continuous, and bottom washing options reduce wash times to a minimum.
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Flexibility
By using automatically-detected, interchangeable 96 and 384 wash heads, the AquaMax washer configures easily to meet current and future, higher-density microplate application requirements.
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Automation
The washer is easy to integrate with the latest automation tools. It is compatible with the Molecular Devices StakMax® Microplate Stacker and many robotic plate handlers.
Save time and money with a
microplate reader and washer bundle

Improve your lab’s efficiency, get more data, and decrease time to discovery with an automated microplate washer and reader solution:
- The SpectraMax® Multi-Mode Microplate Reader provide great flexibility and include absorbance, fluorescence and luminescence with configurable options for TRF and FP and more.
- SoftMax Pro Software is an industry-leading acquisition and analysis software with over 160 ready-to-run protocols, powerful data analysis, and a range of data output options.
- AquaMax® Microplate Washer is a fully self-contained system, configurable for both 96- and 384-well microplates.
- Save on a bundle
Assure data integrity and compliance with confidence
Our comprehensive suite of proven compliance solutions for GMP/GLP labs can advance your efforts to quickly and confidently establish a compliant laboratory.
- Best-in-class microplate readers and washers support all your assay needs
- IQ/OQ/PM services preserve instrument documentation in a digital and compliant format
- Software installation services verify and document that required components are installed to operational specifications
- Software validation service supports FDA 21 CFR Part 11 guidelines
- Validation plates test the performance of your microplate reader using traceable materials for reliable results
- Learn more

Latest Resources
Applications of AquaMax Microplate Washer
Specifications & Options of AquaMax Microplate Washer
Resources of AquaMax Microplate Washer
Blog
[Podcast] Challenges of traditional cell line development and emerging technologies to help regulate monoclonality
[Podcast] Challenges of traditional cell line development and emerging technologies to help regulate monoclonality
Advancements in genetic engineering and synthetic biology have allowed numerous breakthroughs in recent decades. The importance of cell line development needs an honorable mention.…
Application Note
Automation of an organ-on-a-chip assay: automated culture, imaging, and analysis of angiogenesis
Automation of an organ-on-a-chip assay: automated culture, imaging, and analysis of angiogenesis
3D cellular models are increasingly popular in many areas of research because they recapitulate the cellular 3D microenvironment better than cells grown in 2D monolayer.
Publications
Project Profile: Organoid Innovation Center
Project Profile: Organoid Innovation Center
Lab Manager speaks to Dan O’Connor, vice president, drug discovery, Molecular Devices, about the company’s Organoid Innovation Center in San Jose, CA. The center is 180 sq. ft., with…
Publications
Shaping the Future of Organoid Research
Shaping the Future of Organoid Research
Molecular Devices, a provider of innovative life science technology, recently unveiled a brand new, first-of-its-kind Organoid Innovation Center. Situated at the company’s global hea…
Blog
FDA 21 CFR Part 11 and the importance of regulatory compliance in GMP and GLP labs
FDA 21 CFR Part 11 and the importance of regulatory compliance in GMP and GLP labs
The regulations for food and drug in the United States, described in the Title 21 of the Code of Federal Regulations, and the EudraLex Annex 11 in EU, are critical in ensuring safe…
Customer Breakthrough
HCS Pharma uses ImageXpress Micro Confocal Systems for phenotypic screening of physiologically relevant 3D cell models
HCS Pharma uses ImageXpress Micro Confocal Systems for phenotypic screening of physiologically relevant 3D cell models
HCS Pharma is a biotechnology start-up focused on in vitro preclinical research and development. The company specializes in multi-parametric cell imaging assays using High-C…
Application Note
Maximizing cell wash performance with AquaMax 2000/4000 Microplate Washers and cell wash heads
Maximizing cell wash performance with AquaMax 2000/4000 Microplate Washers and cell wash heads
Many cell-based applications, including calcium flux assays and cell-based ELISAs, require gentle but thorough washing of cells in microplates in order to minimize cell loss and ensure…
Application Note
Washing MAGPIX beads with the AquaMax 2000/4000 Microplate Washer and LifeSep magnetic plate holder
Washing MAGPIX beads with the AquaMax 2000/4000 Microplate Washer and LifeSep magnetic plate holder
The MAGPIX multiplexing system offers high-throughput multiplexing capabilities with up to 4800 results in one hour. To ensure optimal performance of these assays, it is essential to…
Data Sheet
AquaMax Microplate Washers
AquaMax Microplate Washers
Learn how the AquaMax Microplate Washer is an adaptable washer capable of improving cell-based assay workflows in both the 96 and 384 well formats.


Enhancing 3D Disease Models: Automated, High-Throughput, Phenotypic Screening with Organ-on-a-Chip

Immunology and Vaccine Development Workflow

AquaMax Microplate Washer
Number of Citations*: 109
Latest Citations: For a complete list, please click here .
*Source: https://scholar.google.com/
- Dated: Dec 01, 2017Publication Name: Muscle Stem Cells
Systematic Identification of Genes Regulating Muscle Stem Cell Self-Renewal and Differentiation
The hallmark of stem cells is their capability to either self-renew or to differentiate into a different cell type. Adult skeletal muscle contains a resident muscle stem cell population (MuSCs) known as satellite cells, which enables regeneration of damaged muscle tissue throughout most of adult life. During skeletal muscle regeneration, few MuSCs… View moreThe hallmark of stem cells is their capability to either self-renew or to differentiate into a different cell type. Adult skeletal muscle contains a resident muscle stem cell population (MuSCs) known as satellite cells, which enables regeneration of damaged muscle tissue throughout most of adult life. During skeletal muscle regeneration, few MuSCs self-renew to maintain the muscle stem cell pool while others expand rapidly and subsequently undergo myogenic differentiation to form new myofibers. However, like for other stem cell types, the molecular networks that govern self-renewal and/or differentiation of MuSCs remain largely elusive. We recently reported a method to isolate sufficient amounts of purified MuSCs from skeletal muscle which enables us to study their cell autonomous properties. Here, we describe a lentiviral, image-based loss-of function screening pipeline on primary MuSCs that enables systematic identification of genes that regulate muscle stem cell function.
- Dated: Feb 15, 2017Publication Name: Nature
Sterile protection against human malaria by chemoattenuated PfSPZ vaccine
A highly protective malaria vaccine would greatly facilitate the prevention and elimination of malaria and containment of drug-resistant parasites1. A high level (more than 90%) of protection against malaria in humans has previously been achieved only by immunization with radiation-attenuated Plasmodium falciparum (Pf) sporozoites (PfSPZ)… View moreA highly protective malaria vaccine would greatly facilitate the prevention and elimination of malaria and containment of drug-resistant parasites1. A high level (more than 90%) of protection against malaria in humans has previously been achieved only by immunization with radiation-attenuated Plasmodium falciparum (Pf) sporozoites (PfSPZ) inoculated by mosquitoes2,3,4; by intravenous injection of aseptic, purified, radiation-attenuated, cryopreserved PfSPZ (‘PfSPZ Vaccine’)5,6; or by infectious PfSPZ inoculated by mosquitoes to volunteers taking chloroquine7,8,9,10 or mefloquine11 (chemoprophylaxis with sporozoites). We assessed immunization by direct venous inoculation of aseptic, purified, cryopreserved, non-irradiated PfSPZ (‘PfSPZ Challenge’12,13) to malaria-naive, healthy adult volunteers taking chloroquine for antimalarial chemoprophylaxis (vaccine approach denoted as PfSPZ-CVac)14. Three doses of 5.12 × 104 PfSPZ of PfSPZ Challenge12,13 at 28-day intervals were well tolerated and safe, and prevented infection in 9 out of 9 (100%) volunteers who underwent controlled human malaria infection ten weeks after the last dose (group III). Protective efficacy was dependent on dose and regimen. Immunization with 3.2 × 103 (group I) or 1.28 × 104 (group II) PfSPZ protected 3 out of 9 (33%) or 6 out of 9 (67%) volunteers, respectively. Three doses of 5.12 × 104 PfSPZ at five-day intervals protected 5 out of 8 (63%) volunteers. The frequency of Pf-specific polyfunctional CD4 memory T cells was associated with protection. On a 7,455 peptide Pf proteome array, immune sera from at least 5 out of 9 group III vaccinees recognized each of 22 proteins. PfSPZ-CVac is a highly efficacious vaccine candidate; when we are able to optimize the immunization regimen (dose, interval between doses, and drug partner), this vaccine could be used for combination mass drug administration and a mass vaccination program approach to eliminate malaria from geographically defined areas.
Contributors: Benjamin Mordmüller, Güzin Surat, Heimo Lagler, Sumana Chakravarty, Andrew S. Ishizuka, Albert Lalremruata, Markus Gmeiner, Joseph J. Campo, Meral Esen, Adam J. Ruben, Jana Held, Carlos Lamsfus Calle, Juliana B. Mengue, Tamirat Gebru, Javier Ibáñez, Mihály Sulyok, Eric R. James, Peter F. Billingsley, KC Natasha, Anita Manoj, Tooba Murshedkar, Anusha Gunasekera, Abraham G. Eappen, Tao Li, Richard E. Stafford, Minglin Li, Phil L. Felgner, Robert A. Seder, Thomas L. Richie, B. Kim Lee Sim, Stephen L. Hoffman & Peter G. Kremsner -Show fewer authors
Go to article - Dated: Nov 01, 2014Publication Name: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
Evaluation of yolk protein levels as estrogenic biomarker in bivalves; comparison of the alkali-labile phosphate method (ALP) and a species-specific immunoassay (ELISA)
Altered concentration of the vertebrate yolk protein precursor vitellogenin is a recognized biomarker for endocrine disruption in fish, and within recent years yolk protein alteration has also been associated with endocrine disruption in bivalves. Species-specific, direct and sensitive methods for quantification of vitellogenin in fish have been… View moreAltered concentration of the vertebrate yolk protein precursor vitellogenin is a recognized biomarker for endocrine disruption in fish, and within recent years yolk protein alteration has also been associated with endocrine disruption in bivalves. Species-specific, direct and sensitive methods for quantification of vitellogenin in fish have been available for years whereas bivalve yolk protein levels have been estimated indirectly by alkali-labile phosphate (ALP) liberated from high molecular weight proteins because the sequence and biochemical structure of most bivalve yolk proteins are unknown. By applying a species-specific enzyme-linked immunosorbent assay (ELISA) for accurate determination of yolk protein level the impact of 17β-estradiol (57, 164 and 512 ng/L) on the freshwater bivalve Unio tumidus was investigated and compared with ALP estimations. Seven weeks of exposure during the pre-spawning and spawning period had no consistent effect on yolk protein concentration in hemolymph, and ALP levels in hemolymph also remained unchanged in both males and females. Further, basal male and female ALP levels were indistinguishable whereas the ELISA demonstrated that yolk protein levels of females exceeded male levels at the time of sampling, although male basal levels were high compared to fish. Altogether it is shown that individual ALP levels do not reflect yolk protein levels and hence hemolymph ALP levels cannot serve as biomarker for estrogenic exposure during the pre-spawning and spawning period in U. tumidus. The necessity of sensitive and validated biomarkers for reliable interpretation of data and the utility of ALP and yolk protein levels as biomarkers in bivalves are discussed.
Contributors: Jane E. Morthorst, Henrik Holbech, Morten Jeppesen, Karin L. Kinnberg, Knud L. Pedersen, Poul Bjerregaard
Go to article
AquaMax® Microplate Washer
Product | Part Number |
AquaMax 2K Bundle includes AquaMax 2000 Microplate Washer, 96-Plate Wash Head, Two Assay Bottles with level sensor, and 10L Waste bottle with sensor
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AQUAMAX 2K
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AquaMax 4K Bundle includes AquaMax 4000 Microplate Washer, 96-Plate Wash Head, Four Assay Bottles with level sensor, and 10L Waste bottle with sensor | AQUAMAX 4K |
StakMax Microplate Handling Stacker
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STAKMAX
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AquaMax Sterilant
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R8156
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On-site Compliance Assurance IQOQ Service for AquaMax 2000 Plate Washers (Installation Qualification/Operation Qualification service including detailed IQOQ results for system owner qualification records)
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AQ2000-IQOQSVC-OS
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On-site Compliance Assurance IQOQ Service for AquaMax 4000 Plate Washers (Installation Qualification/Operation Qualification service including detailed IQOQ results for system owner qualification records)
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AQ4000-IQOQSVC-OS
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Related Products & Services of AquaMax Microplate Washer
Customer Breakthrough


SUCCESS STORY
HCS Pharma uses ImageXpress Micro Confocal Systems for phenotypic screening of physiologically relevant 3D cell models
How can we help advance your next big discovery?
Our highly-qualified teams are on the frontlines with our customers, conducting remote or on-site product demonstrations, webinars, and more to help you solve your tough research challenges. How can we help you today?
I’d like to…
How can we help advance your next big discovery?
Our highly-qualified teams are on the frontlines with our customers, conducting remote or on-site product demonstrations, webinars, and more to help you solve your tough research challenges. How can we help you today?
I’d like to…