Advanced Cloud-Based Analytics with StratoMineR
Increase efficiency and throughput with cloud-based advanced analytics
Advanced Cloud-Based Analytics with StratoMineR
An intuitive and powerful platform for phenotypic profiling
Core Life Analytics' StratoMineR™ software helps biologists analyze the complex data derived from high-content image analysis. A powerful, intuitive workflow allows users to port data analyzed in IN Carta® Image Analysis Software directly into StratoMineR where it is used to generate rich, interactive visualizations using advanced data mining methods.
Features
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Flexible data upload
Numerical data can be uploaded directly from IN Carta Image Analysis Software.
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Artificial Intelligence
Machine learning models can be applied to leverage AI technology in data analytics.
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Phenotypic characterization
Clustering and visualization of cellular phenotypes.
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Quality Control
Use built-in data visualization tools for quick assessment of data quality and remove outliers.
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Reduced data complexity
Data reduction decreases complexity and increases focus on key biological interactions.
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Collaboration
Utilize project management tools for collaboration.
Import datasets from IN Carta for deeper insights into your data
IN Carta Image Analysis Software provides robust, quantitative results from complex biological images and datasets utilizing advanced AI technology. Directly import this data into StratoMineR, an intuitive web-based platform which guides users through a typical workflow in analysis of high-content, multi-parametric data.
Cluster analysis
Cluster analysis: A) A dendrogram representing hierarchical relationships is shown. B) Examples of compound-treated cells belonging to the some of the clusters are shown. Cluster 5 consists of tetrandrine- and chloroquine-treated cells. Cluster 4 consists of rotenone- and paclitaxel-treated cells.
Scatter plot
Example of a scatter plot using HC StratoMineR for visualization and exploration.
ImageXpress® Confocal HT.ai High-Content Imaging System
Powerful multi-laser light sources, a deep tissue penetrating confocal disk module, water immersion objectives and modern machine learning analysis software
- Ideal for highly complex cell-based and 3D assays
- Seven-channel high-intensity lasers generating brighter images with higher signal-to-background ratio
- Spinning confocal disk technology for deeper tissue penetration, resulting in sharper images with improved resolution
- Water immersion objectives offering up to quadruple the signal at lower exposure times for greater sensitivity and image clarity
- View product
IN Carta Image Analysis Software
Modern machine learning, high-content image analysis software
Powerful analytics combined with an intuitive user interface simplify workflows for image analysis and phenotypic profiling. Advanced features provide the functionality you need to analyze data in 2D, 3D, and 4D - at scale - and deliver real-time insights without the need for complex pre- or post- processing operations. Improve specificity of your image analysis workflows by utilizing the SINAP deep-learning module and see for yourself that Segmentation Is Not A Problem. Put machine learning to work for you and perform complex phenotypic analysis within a user-friendly Phenoglyphs module.
Latest Resources
Applications of StratoMineR
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Cell Painting
Cell Painting is a high-content, multiplexed image-based assay used for cytological profiling. In a Cell Painting assay, up to six fluorescent dyes are used to label different components of the cell including the nucleus, the endoplasmic reticulum, mitochondria, cytoskeleton, the Golgi apparatus, and RNA. The goal is to “paint” as much of the cell as possible to capture a representative image of the whole cell.
Cellular Imaging & Analysis
Researchers have several options in methods for imaging cells, from phase-contrast microscopy that shows intact cells to fluorescent imaging of single molecules or organelles. Cellular analysis is performed to evaluate and measure the current state of cells, such as cell integrity, toxicity, and viability and various other research applications. An integral part of cellular analysis is data collection, analysis, and export into a meaningful and useful format.
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Stem Cell Research
Pluripotent stem cells can be used for studies in developmental biology or differentiated as a source for organ-specific cells and used for live or fixed cell-based assays on slides or in multi-well plates. The ImageXpress system has utility in all parts of the stem cell researcher’s workflow, from tracking differentiation, to quality control, to measuring functionality of specific cell types.
Toxicology
Toxicology is the study of adverse effects of natural or man-made chemicals on living organism. It is a growing concern in our world today as we are exposed to more and more chemicals, both in our environment and in the products we use.
Resources of StratoMineR
Publications
Overcoming ‘Analysis Paralysis’ in Cell Painting With Artificial Intelligence
Overcoming ‘Analysis Paralysis’ in Cell Painting With Artificial Intelligence
Gone are the days of only measuring single parameters in cell-based experiments. Instead, researchers should widen their focus, namely with the help of innovations like the Cell Pain…
Scientific Poster
Image-based phenotypic profiling using Cell Painting in a 3D breast cancer spheroid model
Image-based phenotypic profiling using Cell Painting in a 3D breast cancer spheroid model
Most potential oncology drugs fail the drug development pipeline, despite having promising data for their efficacy in vitro. This further incentivize the need for identifying in vitr…
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Publications
AI-Powered Phenotypic Profiling Revolutionizes Drug Discovery
AI-Powered Phenotypic Profiling Revolutionizes Drug Discovery
Today, nine out of ten drugs fail in clinical trials. Furthermore, it takes over a decade and an average cost of $2 billion to develop and approve each…
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Publications
A Picture Paints a Thousand… New Therapies?
A Picture Paints a Thousand… New Therapies?
Cell painting is a high-content profiling technology that uses up to six fluorescent dyes to visualize specific cellular components at the single-cell level. The assay essentially “p…
Brochure
StratoMineR
StratoMineR
Core Life Analytics’ StratoMineR™ software helps biologists analyze the complex data derived from high-content image analysis. A powerful, intuitive workflow allows users to port dat…
Application Note
Increase Cell Painting assay throughput using an automated workstation
Increase Cell Painting assay throughput using an automated workstation
Cell painting has become a popular screening method within the drug discovery community. This phenotypic screening platform leverages advances in high-content microscopy, high-…
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Application Note
Improving the robustness of Cell Painting with a near-infrared label and advanced image and data analytics
Improving the robustness of Cell Painting with a near-infrared label and advanced image and data analytics
Image-based phenotypic profiling approaches such as the widely used Cell Painting assay use high-content imaging along with multiparametric readouts to study biological, genetic, and…
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Scientific Poster
Simplified workflow for phenotypic profiling based on the Cell Painting assay
Simplified workflow for phenotypic profiling based on the Cell Painting assay
Multiparametric high-content screening approaches, such as the Cell Painting assay, are increasingly being used in many applications ranging from drug discovery programs to functiona…
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Application Note
High-content phenotypic profiling using the Cell Painting assay
High-content phenotypic profiling using the Cell Painting assay
Here, we present a complete workflow for a cell painting assay that can be easily implemented using the ImageXpress Micro system and image analysis with machine learning capabilities
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Brochure
Innovative Solutions for Drug Discovery and Life Sciences Research
Innovative Solutions for Drug Discovery and Life Sciences Research
Molecular Devices is a leading provider of high-performance bioanalytical measurement solutions for life science research, pharmaceutical development, and biotherapeutic discovery. O…
Videos & Webinars
3D Imaging Seminar Series
High-Content Phenotypic Screening
Emerging Organoid Models: Translating Basic Research to Drug Development and Regenerative Medicine
Related Products & Services of Cloud-Based Advanced Analytics by StratoMineR
Acquisition and Analysis Software
IN Carta Image Analysis Software
Provides robust, quantitative results from complex biological images and datasets
Featured Applications
Cell Painting
Cell Painting is a high-content, multiplexed image-based assay used for cytological profiling. In a…
Cellular Imaging & Analysis
Researchers have several options in methods for imaging cells, from phase-contrast microscopy that…
Stem Cell Research
Pluripotent stem cells can be used for studies in developmental biology or differentiated as a…
Toxicology
Toxicology is the study of adverse effects of natural or man-made chemicals on living organism. It…
How can we help advance your next big discovery?
Our highly-qualified teams are on the frontlines with our customers, conducting remote or on-site product demonstrations, webinars, and more to help you solve your tough research challenges. How can we help you today?
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