Octet K2 System

The Octet® K2 2-channel System brings you unprecedented access to exquisite biomolecular interactions data. Priced for startup academic and biotech labs, low volume users are no longer bound by the trade-off between cost and performance when choosing a label-free assay system. The Octet K2 System characterizes protein-protein and protein-small molecule binding interactions for early research and discovery. The multipurpose system also provides quantitative information by measuring active protein concentrations — even in complex mixtures like cell culture supernatants and lysates.

  • Sensitivity for small molecule analysis

    Sensitivity for small molecule analysis

    The Octet K2 System enables the measurement of interactions between small molecules down to 150 Da in size, and their larger binding partners to determine accurate kinetics rates.

  • Flexible second channel

    Flexible second channel for use as a reference or more samples

    Unique 2-channel design have dedicated spectrometers for simultaneous referencing or added capacity.

  • Simple setup for protein and antibody

    Simple setup for protein and antibody characterization

    Template driven interface allows new users to get started quickly for protein and antibody characterization.

Features

  • Kinetic analysis

    Kinetic analysis

    The Octet K2 System monitors binding events in real time to calculate on rates (ka), off rates (kd), and dissociation constants (KD). The system's two channels can be used to measure samples independently or in tandem, pairing the sample read with a dedicated reference. Samples are loaded in standard microplates, eliminating fluidic line maintenance and expanding the number of samples that can be run in an assay. With predefined templates to follow in Octet data acquisition software, the system streamlines setup prior to running an assay and minimizes training needs. The software then gives users a range of parameters and metrics for analyzing acquired data in a powerful yet intuitive software interface.

  • Quantitative measurements

    Quantitative measurements

    Utilizing ForteBio's one-step Dip and Read™ assays, the Octet K2 System directly measures the presence of specific proteins and other molecules in solution. Accurate and reproducible concentrations can be determined in as little as two minutes per sample.

  • Biosensor reracking

    Biosensor Re-racking

    The Octet K2 System provides the ability to rerack biosensors at the end of an experiment. Biosensor reracking provides enhanced flexibility in loading ligands on biosensors and reduces operational costs when biosensors are loaded with precious target reagents.

Applications for Entry Level Octet System – Octet® K2 System

  • Large Molecule Characterization

    Large Molecule Characterization

    With pre-defined templates to follow in Octet Data Acquisition software, the Octet K2 system streamlines setup prior to running an assay and minimizes training needs. Octet Data Analysis software then gives users a range of parameters and metrics for analyzing acquired data, in a powerful yet intuitive software interface

    Read Application Note  

  • Small Molecule Characterization

    Small Molecule Characterization

    The Octet K2 system monitors binding events in real time to calculate on rates (ka), off rates (kd), and dissociation constants (KD). The system's two channels can be used to measure samples independently or in tandem, pairing the sample read with a dedicated reference.

    Read Application Note  

Specification & Options of Octet® K2 System

Resources of Entry Level Octet System

Videos and Demos

Cell-based Label-free Monitoring of Signal Transduction

Cell-based Label-free Monitoring of Signal Transduction

Fast and Flexible Analysis of Fc-Gamma Receptor Binding Interactions

Fast and Flexible Analysis of Fc-Gamma Receptor Binding Interactions

Flexible Monitoring of Small Molecules with Aptamer Affinity Reagents Using Bio-Layer Interferometry

Flexible Monitoring of Small Molecules with Aptamer Affinity Reagents Using Bio-Layer Interferometry

Kinetics on the Octet Systems

Kinetics on the Octet Systems What Lies Beneath the Curves

 Large Molecule Kinetic Assays

Best Practices for Large Molecule Kinetic Assays on the Octet System

Protein Concentration Measurements

Protein Concentration Measurements in Crude Samples in a Dip and Read Format

The Octet Platform

The Octet Platform A Versatile Instrument in Downstream Processing

Epitope Binning Assays on Octet HTX

Cross-competition or Epitope Binning Assays on the Octet HTX System

Related Products & Services of Entry Level Octet System – Octet® K2 System

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We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.

Ready to get started?

We are ready to help you solve your tough research challenges. Our proven solutions and highly qualified teams across the globe can help advance your next big discovery.