Neurotransmitter Transporter Uptake Assay Kit

Until recently, radioactively labeled compounds were used to measure serotonin, norepinephrine and dopamine transporter uptake. With the introduction of the Neurotransmitter Transporter Uptake Assay Kit, researchers now have a tool to screen for live-cell kinetic uptake for these three key neurotransmitters.

  • Homogeneous, live-cell fluorescent assay replaces radioactive assays, reducing disposal costs and eliminating safety risks associated with radiolabeled assays
  • One-step, homogeneous assay format is amenable to automation and high-throughput screening
  • Two assay setup options offer greater flexibility: endpoint mode for high-throughput applications, or real-time kinetic mode for mechanistic studies

Technology of Neurotransmitter Transporter Uptake Assay Kit

  • Assay principle-Neurotransmitter

    Assay principle-Neurotransmitter

    The Neurotransmitter Transporter Uptake Assay Kit uses a fluorescent substrate that mimics the biogenic amine neurotransmitters and is taken into the cell through those specific transporters, resulting in increased intracellular fluorescence intensity that is monitored in real time using a bottom-reading microplate reader. In this convenient no-wash procedure, cells are incubated with the kit reagent and transferred to the plate reader for evaluation. The assay is ideal for use in academic, biotech, and pharmaceutical environments for research, assay development, and screening.

  • Workflow-Neurotransmitter

    Workflow-Neurotransmitter

    For more details, please refer to the Neurotransmitter Transporter Uptake Assay Kit product insert, which may be accessed through the Molecular Devices Knowledge Base.

Ordering Options of Neurotransmitter Transporter Uptake Assay Kit

Neurotransmitter Transporter Uptake Assay Kit

Evaluation Kit

  • 1 vial = 1 plate x 2 vials each

#R6138

$164.00 USD

1

Explorer Kit

  • 1 vial = 1 plate x 5 vials

#R8173

$629.00 USD

1

Bulk Kit

  • 1 vial = 10 plates x 5 vials

#R8174

$4,500.00 USD

1

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